Multicentric Reticulohistiocytosis, A Rare Cause of Polyarthritis with Skin Manifestations in Paediatric Age Group: A Case Report
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 12
Abstract
Backgound: Multicentric reticulohistiocytosis is a rare proliferative histiocytic disease of unknown etiology with potentially disabling nature. Primary manifestations are involvement of skin as paulonodular leisons and arthritis . The articular destruction can lead to permanent joint deformities. Case Presentation: Our patient is a 11 year old boy presented with polyarthritis and reddish- brown papulonodular cutaneous lesions. The diagnosis of multicentric reticulohistiocytosis was confirmed by histopathological examination of skin nodules that was further substantiated by immunohistochemistry. The boy responded with oral corticosteroids and subcutaneous methotrexate injection. Conclusion: Though Multicentric reticulohistiocytosis (MRH) is a rare condition in pediatric patients, but it is with potentially disabling nature, timely diagnosis and treatment with immunosuppressant can controll this disease process.
Authors and Affiliations
Dr Hriday De
Keywords
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