MULTIPLE ORGAN FAILURE IN THE PRACTICE OF PEDIATRIC RESUSCITATION: UPDATED PATHOPHYSIOLOGY AND PROGNOSIS
Journal Title: International scientific journal Science and Innovation - Year 2023, Vol 2, Issue 12
Abstract
Multiple organ failure is a leading cause of admission to the intensive care units, characterized by a high case fatality rate and significant financial costs. Here we review the mechanisms of multiple organ failure in pediatric patients (triggers, concomitant diseases, release of danger- and pathogen-associated molecular patterns, bacterial translocation, epithelial, endothelial, or mitochondrial dysfunction, and inadequate immune response) and recent diagnostic and prognostic scales.
Authors and Affiliations
G. M. Tulegenova
Keywords
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- DOI 10.5281/zenodo.10275495
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