MULTIPLE UNIT PELLET SYSTEM (MUPS TECHNOLOGY) FOR DEVELOPMENT OF MODIFIED RELEASE FAST DISINTEGRATING TABLETS: A REVIEW
Journal Title: Journal of Pharmaceutical and Scientific Innovation - Year 2017, Vol 6, Issue 3
Abstract
Oral drug delivery system becomes challenging when the drug product needs to be delivered in modified release pattern in elderly patients, especially since it is difficult to swallow for them. Multiparticulates are the choice of dosage form when fast disintegration is desirable without loss of original release profile. Compressed multi-particulate system prepared by using pellets have several pharmacokinetic, pharmacodynamic, commercial and other advantages as mentioned henceforth in this review article. It includes not only different types of modified release pellets that can be compressed into Multiple Unit Pellet System (MUPS) but also factors regulating the compression behavior of pellets including properties of pellets, core material, and compressible excipients. This review also presents detailed explanation on physicochemical properties of pellets and formulation strategies of MUPS.
Authors and Affiliations
Nrupa G. Patel, Sandipkumar A. Patel, Abhijeet B. Joshi
Keywords
Related Articles
- EP ID EP614934
- DOI 10.7897/2277-4572.06352
- Views 59
- Downloads 0
DETERMINATION OF SUITABLE METHOD OF PREPARATION OF MICROCAPSULES FOR BOTH WATER SOLUBLE AND INSOLUBLE DRUG
In recent years, wide varieties of newer oral drug delivery systems are designed and evaluated in order to overcome the limitations of conventional therapy. Different studies have shown the feasibility of alginate-based...
PURIFIED WATER FROM URINE: A REVIEW
Even if, urine mostly consists of water it’s not suitable for consuming. But now a number of techniques were developed for converting urine into purified water. The main fields were urine is used as drinking water is int...
A BIRD VIEW ON BASIC AYUR ASTROLOGY
Ayurveda and Vedic Astrology both are derived from Veda. Vedic Astrology is an ancient science which hasbeen universally accepted and is timeless,whereas Ayurveda is called “The mother of all healing” Ayurveda explores t...
AN EFFECTIVE AYURVEDA TREATMENT FOR A REPAIRED THIRD DEGREE INFECTED PERINEAL TEAR: A CASE REPORT
Perineal trauma can be considered as any type of damage to the female genitalia during labour, which occurs spontaneously or iatrogenically.The incidence of perineal trauma worldwide is 84.3% of which 95% of primiparous...
ASSESSMENT OF ANTHELMINTIC ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF PSIDIUM GUAJAVA LEAVES: AN IN-VITRO DESIGN
Back ground: In the recent years, the use of herbal products has been increasing in developing countries. Psidium guajava Linn. (Guava), family: Myrtaceae is an important dietary plant used traditionally for medicinal pu...