Multipronged diagnostic approaches for monitoring the treatment of Brucella abortus infected patient: a case report
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2015, Vol 5, Issue 7
Abstract
Brucellosis caused by Brucella species is readily transmissible to humans, causing acute febrile illness and undulant fever which may progress to a more chronic form and can also produce serious complications affecting the musculoskeletal, cardiovascular, and central nervous systems. A veterinary livestock inspector presented to the institute with symptoms of intermittent fever, pain involving muscles and joints, loss of weight, anxiety and weakness for about three months has been investigated. The isolation, serological tests and PCR were performed for diagnosis of brucellosis. Based on history of constant professional association with animals, characteristic symptoms, hematological and biochemical, multiple serological and PCR assay results, the patient was diagnosed as brucellosis. Detection of Brucella abortus directly in the clinical samples by gel based PCRs were highly useful for diagnosis and monitoring of treatment. This diagnostic protocol will facilitate in a simple way to map major Brucella species infecting humans in a geographical region.
Sero-prevalence of brucellosis among blood donors in Ahvaz, Southwest Iran
Objective: To identify sero-prevalence of brucellosis among blood donors in Ahvaz city, Southwest Iran. Methods: A total number of 1 450 serum samples from blood donation were collected and were screened for the presence...
Peptide-assembled graphene oxide as fluorescent turn-on sensor for ultrasensitive Lipopolysaccharide (Endotoxin) detection
Introduction: Lipopolysaccharide (LPS), or endotoxin, a major component in the outer cell membrane of Gram-negative bacteria is a very powerful and toxic inflammatory stimulator, resulting in sepsis or septic shock, a si...
Evaluation of Helicobacter pylori infection and other risk factors in patients with benign peptic ulcer disease
Objective: To assess and compare the risk factors in patients with benign gastric and duodenal ulcers and to correlate the prevalence of Helicobacter pylori (H. pylori) infection in benign peptic ulcer disease. Methods:...
Acute fulminant myocarditis in a case of dengue fever: A case report
Dengue is one of the most important mosquito-borne viral diseases in the world. Of note, a variety of cardiac complications have been reported in dengue-affected patients. We reported a 5-year-old boy who presented with...
The recent outbreaks of Zika virus: Mosquito control faces a further challenge
The recent outbreaks of Zika virus infection occurring in South America, Central America and the Caribbean, represent the most recent of four key arrivals of arboviruses in the Western Hemisphere over the last 20 years....