Multisession CyberKnife Radiosurgery for Symptomatic Abducens Nerve Palsy
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2019, Vol 16, Issue 4
Abstract
Abducens nerve palsy causes diplopia which lowers patients’ quality of life. Nerve palsy due to tumor compression is treated by surgery, but Abducens nerve is difficult to access. Ten patients with benign and malignant tumors in cavernous sinus and cliva were involved in this study: trigeminal schwannoma, meningioma, cavernous hemangioma, metastatic tumors from prostate, breast, and uterus cancer. They were treated with multisession CyberKnife radiosurgery on outpatient bases. Diplopia was treated in all the patients, without any significant adverse effects. The longest follow-up was over 10 years, with all patients leading normal lives. This is the first study to evaluate the use of CyberKnife radiosurgery for the treatment of diplopia. There are many causes for Abducens nerve palsy. Diplopia due to Abducens Nerve palsy not only causes mental distress to the patients but also lowers quality of life (QOL) in disablement of reading and writing. Nerve palsy due to compression by tumor can be treated by removing or downsizing the tumor, usually with surgery or radiation therapy. Abducens nerve is in the deep part of the brain which is difficult to reach. Standard surgery is either impossible or harmful, while standard radiation therapy takes several weeks of treatment. The CyberKnife system (Accuracy Incorporated, Sunnyvale, California) is a robotic radiosurgery system that provides highly precise stereotactic body radiotherapy (SBRT). SBRT with CyberKnife is far less invasive compared to standard surgery, can be completed within 1 week, and hospitalization is not required. Abducens nerve palsy due to tumor is shown to be sufficiently treated by CyberKnife.
Authors and Affiliations
Yuko Harada, Shinichiro Miyazaki
Keywords
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- EP ID EP587446
- DOI 10.26717/BJSTR.2019.16.002895
- Views 172
- Downloads 0
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