Mutual Predators: A Descriptive Cross-Sectional Study to Identify Prevalence of Hepatitis C Virus and Human Immunodeficiency Virus Type-1 Mono and Co-Infection
Journal Title: International Journal of Science and Research (IJSR) - Year 2015, Vol 4, Issue 2
Abstract
Abstract: Coinfection, bacterial or viral origin, in HIV infected individuals’ remains to be the only leading cause of deaths. This study was designed to analyze received plasma samples and plasma samples of referred patients for HIV testing to detect HIV and HCV mono and co-infection by real time PCR and finding co-relation of viral load of both viruses. Highlight and magnify the hidden coinfection, prior to seroconversion, of HIV type-1 and Hepatitis C Virus in received samples. Methods: Analyses were based on randomly selected 78 patients’ stored plasmas. Plasma samples were tested for both, HIV-type 1 and HCV viral RNA by real time PCR. Statistical formulas were used to identify mean and the inter quartile range of patients age. The data were analyzed by IBM SPSS Statistics 21 (SPSS Inc., Chicago, IL). Study variables include gender, age and viral loads of HIV type-1 and HCV. Pearson correlation was used to evaluate any correlation in study variables. Result: Prevalence of HCV was 10.3%, HIV-type 1 was 19.2% and their co-infection was 37.2 percent. Thirty three percent individuals had no infection of both viruses. Gender based distribution showed that 74.4% (58/78) sample population was male. The mono-infection and co-infection was higher in males (39.7%) and highest viral load too. There was a positive correlation (CI= 95%) between the two variables; HIV and HCV viral loads, as r = 0.736, n=29, p= 0.001. Conclusion: Prevalence of HIV type-1 and HCV mono-infection and co-infection was higher among males as compared to females. Increased viral load was also evident among male co-infected individuals. This study proved the emergence of HCV coinfection in HIV infected individuals, and a need for on time diagnosis and treatment.
Spontaneous Rupture of Unscarred Uterus in Grand Multiparous Women: A Report of 5 Cases
Introduction: Uterine rupture is a catastrophic obstetrical emergency associated with a significant foeto-maternal morbidity and mortality. Many risk factors for uterine rupture have been identified, as well as a wide ra...
Comparison of Financial Performance of State Owned Commercial Banks: A Case Study of Bangladesh
Comparison of Financial Performance of State Owned Commercial Banks: A Case Study of Bangladesh
Design and Analysis of Chassis and Body in White (BIW) in Automation Using Six-Sigma and Optimization Techniques
A chassis composed of an internal framework that holds up a man-made object in its production and use. An example of a chassis is the under part of a motor vehicle, consisting of the frame. If the running gear such as wh...
Design of Student Formula Race Car Chassis
"SUPRA SAEINDIA is an annual national level competition organized by the Society of Automotive Engineers India. From all over India, the selected Under Graduate & Post Graduate Engineering Student teams are asked to desi...
Effect of Return on Assets (ROA) Against Tobin's Q: Studies in Food and Beverage Company in Indonesia Stock Exchange Years 2007-2011
This study aimed to determine the effect of Return On Assets (ROA) to Tobin's Q, populations to be studied in this research is a food and beverage are included in the Indonesia Stock Exchange (BEI) in 2007-2011, the time...