Mycoplasma pneumonia infection in Cancer Patients at a Regional Cancer Center, South India
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 4
Abstract
Purpose: Mycoplasma pneumoniae (M.pneumoniae) forms one of the major causes of the community acquired respiratory infections in paediatric and adult populations. A prospective study was done to evaluate the frequency of M.pneumoniae infections in cancer patients at a regional cancer hospital in South India. Materials and Methods: Blood was sampled from 65 adult patients with confirmed solid and haematological malignancies during febrile episodes. Serological estimation for IgM antibodies to M. pneumoniae was done using IgM enzyme – linked immunosorbent assay (ELISA) kit (EuroImmun, Germany). Thirty age and sex matched normal healthy adult subjects served as control. Results: The breakup of the patients was as follows: Of the 65 patients 51(78.46%) were males and 14 were females (21.53%). Of the total number studied 51(78.46%) had solid tumor while 14 (21.53%) patients had haematological malignancy. Patient who received chemotherapy alone were 18 (27.69%) radiotherapy 14 (21.53%);surgery 10(15.38%); chemotherapy and radiotherapy16(24.61%); chemotherapy and surgery 3(4.61%); radiotherapy and surgery 3 (4.61%); chemotherapy and radiotherapy and surgery1(1.53%). Only one female patient of squamous cell carcinoma post cricoid had IgM antibodies to M. pneumoniae. Two of the 30 control sera were also positive for IgM antibodies to M. Pneumonia Conclusion: From our study we inferred that the frequency of M.pneumoniae infections amongst cancer patients at our centre is infrequent and low. However, detection of IgM antibodies by serological assay is not the only ideal test to know the true frequency of M.pneumoniae infection.The actual frequency could be assessed by simultaneous detection of M.pneumoniae DNA in the sputa along with detection of IgM during febrile episodes
Authors and Affiliations
Sumathi B. G
Keywords
Related Articles
- EP ID EP213569
- DOI -
- Views 69
- Downloads 0
Histiod Leprosy-How Is It Different From Lepromatous Leprosy?-A Case Report
Histoid leprosy, a rare variant of lepromatous leprosy has characteristic clinico- pathological manifestations .We present this case due to their rarity, atypicality of dermal lesions, failure in early diagnosis, and hig...
A Hospital Based Comparative Study on Effect of Lipid Profile in Patients Treated with Older and Newer Anti Epileptic Drugs
Objective: To study the effect of commonly prescribed anti epileptic drugs as Carbamazepine, Phenytoin and newer antiepileptic drug as Lamotrigine, Levetiracetam on lipid profile of epileptic children (2-12 yrs) who had...
Concomitant Esotropias- An Analytical Study
Purpose: To report the incidence of various clinical types, predisposing factors and associations of concomitant esotropias. Design: Prospective randomized population based study. Materials & Methodology: 100 patients wh...
Clinical Profile of Febrile Neutropenia in Children with Acute Leukemia
Introduction: Febrile neutropenia is the most common cause of morbidity and mortality in leukemic patients. These children mostly require parenteral antibiotics because an absolute neutrophil count <500 cells/mm3 conferr...
To assess the prevalence of dry eye disease in postmenopausal females in a tertiary care centre in Central India
Dry eye is disorder due to deficiency of tear film and is common amongst postmenopausal women. Aim is to establish occurrence and prevalence of dry eye in postmenopausal women in tertiary care centre in Central India. A...