Mycotic infections in diabetic foot ulcers in Emam Reza hospital, Mashhad, 2006-20
Journal Title: Jundishapur Journal of Microbiology - Year 2011, Vol 4, Issue 1
Abstract
Introduction and objective: Diabetic foot is the result of uncontrolled diabetes and imperfect sanitary care which leads to necrotic lesions, gangrene and finally amputation. Secondary mycotic infections play a principal role to produce chronic lumpy lesions. This study was designed to investigate the incidence of fungal pathogens in diabetic foot infections. Materials and methods: The study population included 120 consecutive diabetic patients who were hospitalized in the department of vascular surgery due to diabetic foot during 2006-2008. Direct fresh smear and fungal culture were performed for each patient. Fungal contaminations were confirmed by direct microscopy and/or culture. Results: The ages of the patients were between 32 to 86 years old. Of those 86(71.7%) individuals were male and 34(28.3%) were female. Direct examinations in 10% KOH were positive for fungal element in 25(20.8%) cases, but cultures were positive in 30(25%) cases. Candida species were the most predominantly isolated fungi (23 patients). Dermatophytic infection due to Trichophyton mentagrophytes was observed in three cases. The isolated opportunistic molds were known as Acremonium spp., Aspergillus fumigatus and Scopulariopsis spp. Significant correlation was found between infection, gender and age of the patients (P=0.0001 and P=0.0001). Conclusion: This study shows that fungal infection can be observed in about more than 20% of diabetic foot and causes a lesion with poor prognosis. The most common cause of mycotic diabetic foot is different species of Candida spp., especially C. albicans.
Authors and Affiliations
Saba Fata, Mohammad Hadi Saeed Modaghegh, Rabe'eh Faizi, Mohammad Javad Najafzadeh, Monavvar Afzalaghaee, Mohsen Ghasemi, Mohammad Mohammadian, Ali Naseri, Mojtaba Meshkat, Abdolmajid Fata
Keywords
Related Articles
- EP ID EP150067
- DOI -
- Views 119
- Downloads 0
Hepatitis C infection: a review on epidemiology and management of occupational exposure in health care workers for general physicians working in Iranian health network setti
Hepatitis C virus (HCV) infection is a major public health in Iran as well as throughout the world. Health care workers (HCW) are occupationally at the risk of HCV infection. The aim of this article is to review the info...
Detection of Salmonella strain by rapid-cycle multiplex PCR
Introduction and objective: Salmonellosis is responsible for large numbers of infections in both humans and animals. Conventional methods of isolation of Salmonella strains take 4-7 days to complete and are therefore lab...
Frequency of extended-spectrum beta lactamase positive and multidrug resistance pattern in Gram-negative urinary isolates, Semnan, Iran
Introduction and objective: Monitoring of the antimicrobial susceptibilities provides information about patho¬genic organisms isolated from patients, and assists in choosing the most appropriate empirical antimicrobial t...
Investigation of some heavy metals toxicity for indigenous Acidithiobacillus ferrooxidans isolated from Sarcheshmeh copper mine
Introduction and objective: Today mining operations in the metallurgy generate secondary products which cannot be used directly in the basic technology. The mineral industry is increasingly faced with the need to process...
Comparative nitrogen fixation by mesophilic (HTS) vis-à-vis thermotolerant mutants (HTR) of Azotobacter chroococcum at high temperature and their effect on cotton biomass
Introduction and objective: The amount of nitrogen fixed by Azotobacter varied from 0.02-0.25 KgN/ha/d and has been reported to be variable with various physiological and environmental factors. The nitrogen fixation by m...