Myelomatous Pleural Effusion Case report and review of the literature
Journal Title: Sultan Qaboos University Medical Journal - Year 2011, Vol 11, Issue 2
Abstract
Plasma cell myeloma is an uncommon disease which, besides primarily involving the bone marrow, has a tendency to involve other organs thus presenting with different clinical manifestations. While pleural effusions are infrequent in this disease, true myelomatous pleural effusions are extremely rare. We report the case of a middle-aged Omani man with relapsed plasma cell myeloma who developed bilateral pleural effusions. Te diagnosis of myelomatous pleural effusion was made by fnding many abnormal plasma cells as well as a high level of a monoclonal protein (IgG κ) in the pleural fluid. In spite of a good initial response to therapy, the patient had progressive disease and died 6 months later with bacterial sepsis. We present a review of the literature that indicates the rarity of such a manifestation and its association with poor prognosis and short survival.
Authors and Affiliations
Khalil Al-Farsi| Departments of Haematology, Sultan Qaboos University Hospital, Muscat, Oman, Ibrahim Al-Haddabi| Departments of Pathology, Sultan Qaboos University Hospital, Muscat, Oman, Nafla Al-Riyami| Departments of Biochemistry, Sultan Qaboos University Hospital, Muscat, Oman, Rashid Al-Sukaiti| Departments of Radiology & Molecular Imaging, Sultan Qaboos University Hospital, Muscat, Oman, Salam Al-Kindi| Departments of Haematology, Sultan Qaboos University Hospital, Muscat, Oman
Keywords
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