Myocardial Degeneration, Subtypes of CVD and NonCVD – Associations with Fertilization, Selenium Availability, Livestock Fodder and Sugar consumption in Finland during 1971-2012
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2019, Vol 18, Issue 4
Abstract
Pig heart muscle (Myocardial) Degeneration (MyCD) was efficiently treated since the 1960’s with Selenium (Se), but there are scanty published data on human MyCD. Mineral Fertilization (fm) Parameters, including (P/Mg).fm, have often explained less CHD (Coronary Heart Disease) than Non-CHD (others than CHD), but about similarly CVD (Cardiovascular Diseases) and Non-CVD (others than CVD). This study is treating (mortality from) MyCD, CVD and its subtypes: CHD, “cardiac diseases others than CHD” ([Card.oth]), Cerebrovascular (CbrVasc) and other Vascular Diseases ([Vasc.oth]) of Whole Population (WP) and aged 15-64 (15_64), as well as their associations with (P/ Mg).fm, (CaMgNPK).fm, silage production (availability of vitamin E) and human sugar consumption, based on old data. Associations, as concerning Se, are mainly represented by figures, but [Card.oth] and its subtype MyCD are represented by regressions, too. Fertilizer data are slightly smoothened. Results: CHD. (WP) deviated positively from CVD for the whole period, CHD. (15- 64) positively before 1993 and after 1996 negatively. Others deviated mainly negatively. [Card.oth]’s (and [Vasc.oth]’s to a lesser amount) behaved like mirror-images to CHD. [CbrVasc] behaved like CVD. Non-CVD. (15_64) epidemic (1984-94) associated with peak of CaMgNPK with a small delay. Non-CVD. (WP) caused ca 41,000 extraordinary deaths in 1982-2000. MyCD and [Card.oth] were explained (54.8 – 90.7 %) (p < 0.001) by [P/Mg], [P/Mg;CaMgNPK], [Sugar] and [Silage]. Suspected Se changes are seen after 1985-86. Conclusion: Fertilization parameters, sugar consumption and silage production explained changes in MyCD and [Card.oth].(15_64) by 55-91 % (p< 0.001). Reduction in [Card.oth], CbrVasc and [Vasc.oth] was faster than in CHD before 1991. Epidemic of Non-CVD associated with maximal total/carbonate fertilization.Heart muscle (Myocardial) degeneration (MyCD) was efficiently treated by pigs since the 1960’s, but little or nothing has been published on human MyCD [1], if surgical treatments (on an average 16 transplantations annually to adult patients in 1985-2012) [2] are excluded. K/Mg and P/Mg fertilization ratios have associated differently with (mortality from) CHD and Non-CHD [3,4]. Available linear regression (numerical) analyses by fertilizer factors have not anyhow satisfactorily explained mortality difference between CVD and Non-CVD [5]. Historical data shows that fatal pig MyCD was practically ceased before 1971 through improved grain harvesting and postharvesting methods and fodder Se supplementation [6]. Anyhow Se content of human diet was unsatisfactory (29 mcg/d) still at the mid 1970´s [7]. Se fertilization since autumn 1984 elevated Finnish dietary and body content to satisfactory level [8]. 1986 was the first year, when domestic food and fodder were Se enriched from January to December. It was suspected that the changes in cattle fodder could have had effects on human mortality.
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Töysä T
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- EP ID EP621830
- DOI 10.26717/BJSTR.2019.18.003171
- Views 152
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