Myocardial revascularization in patients with coronary artery disease and diabetes mellitus
Journal Title: Moldovan Medical Journal - Year 2018, Vol 61, Issue 4
Abstract
Background: Diabetes mellitus (DM) is one of the most crucial risk factors for morbidity and mortality from coronary heart disease (CAD) in the contemporary world. The prevalence and rapid progression of atherosclerotic lesions leading to worse survival is a defining feature of the course of CAD in patients with DM. Clinical manifestations of CAD often call for revascularization in patients with DM. The contemporary data regarding efficacy of the coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in patients with CAD and concomitant DM are summarized in the review. Conclusions: Worse survival prognosis in case of CAD with concomitant DM is associated with systemic atherosclerosis, presence of a number of concomitant risk factors, as well as masked clinical manifestations of ischemia and myocardial infarction common for the patients with DM. The combination of CAD and DM once again proves the benefit of the long-term use of drugs for the secondary prevention of cardiovascular events. From the standpoint of evidence-based medicine the optimal method of revascularization in CAD patients with multivessel coronary artery disease and concomitant DM is CABG surgery. In FREEDOM study surgical myocardial revascularization reduced the number of endpoints compared to PCI. In the case of PCI it is advisable that eluting stents reducing the likelihood of restenosis and the need for repeated revascularization be used.
Authors and Affiliations
Оlga Yepanchintseva, Оleg Zharinov, Elena Onishchenko, Borys Тоdurov
Keywords
Related Articles
- EP ID EP479462
- DOI 10.5281/zenodo.2222317
- Views 319
- Downloads 0
Markers of the oxidative stress and antioxidant system in pulmonary drug susceptible and drug resistant tuberculosis
Background: The oxidative stress biomarkers in tuberculosis were studied, but the differences between the pulmonary drug susceptible and drug resistant forms were not identified. Material and methods: A prospective, case...
Metabolic syndrome as a risk factor for ischemic stroke
Background: Ischemic stroke is the leading cause of disability and a major cause of mortality worldwide. It is predominantly seen in the elderly and in patients with the metabolic syndrome (MS) [1, 2]. Material and metho...
Medical-economic reasonings on the reform in the field of state surveillance of public health
Background: The functional organization of the service, institution or organization requires adjustment to challenges of the social, economic, and professional environment that intervene development stages of society. Th...
Infravesical urinary tract obstruction and transurethral endoscopic approach of treatment
Backqround: The results of scientifical progress in recent years have contributed to the development of transurethral endoscopic surgery, with the implementation of new methods, less invasive, for the treatment of the lo...
Limited internal fixation in the distal metaepiphyseal shin fractures
Background: The scientific papers deal with it reporting different treatment technologies for distal tibia metaepiphysis fractures; meanwhile the complication and failure rates remain high. Material and methods: 265 pati...