NARINGIN REVEALS AMELIORATIVE PROPERTY OVER ELEVATED OXIDATIVE STRESS LEVELS IN ANIMAL MODELS
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2018, Vol 11, Issue 12
Abstract
Oxidative stress (OxiS) has been implicated in the pathogenesis of many diseases. Free radicals interact with different cell components including DNA, proteins, and lipids to become stable. In this process, these free radicals damage the integrity of these biological moieties and result in various health implications. Naringin (NG), a naturally occurring phytochemical commonly found in grapefruit juice has been explored for its protective role against OxiS. In this short review paper, an attempt has been made to compile the study reports revealing the antioxidative nature of NG in different animal models. Studies have reported NG as a potential antioxidant in various health ailments including diabetes, cardiac fibrosis, cognitive dysfunction, and neurodegeneration.
Authors and Affiliations
Zorawar Singh, Adeshwinder Kaur, Shivam Sharma
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