Nasal Trauma in Neonates receiving CPAP And its Prevention in tertiary care hospital.
Journal Title: Journal of Medical Sciences - Year 2017, Vol 20, Issue 2
Abstract
Objectives: This study was done to evaluate the frequency and severity of nasal trauma secondary to nasal continuous positive airway pressure (NCPAP) in neonates and different methods to reduce the nasal septum injury via CPAP Methods: This is a prospective study carried out in the Neonatal Care Unit (NCU) of LAL DED maternity hospital associated with the department of pediatrics Government Medical College, Srinagar, Kashmir. The study included newborns that underwent NCPAP with prongs on admission and those receiving NCPAP after weaning from ventilator, from 1st January 2016 - 1st jan 2017. Neonates' noses were monitored from the first day of NCPAP treatment until its weaning. Nasal trauma was reported into Three Grades: (I) Erythema/pressure indentation (II) superficial Erosion and (III) Septal necrosis. Results:-258 newborns were included in the study, 136 males, and 122 females. All enrolled newborn received CPAP. Babies were randomly allocated to different groups in which no barrier and different barriers were applied. Randomization of group of infants who received no barrier(group 0) and different barriers( group 1,2,&3) was done by systematic allocation, in which first newborn was randomly designated to no barrier group 0 on particular day of admission ,and subsequently alternating with other three groups i.e group 1,group 2, group 3. The mean gestational age, birth weight and CPAP days in each group is 31wk (GA28-35 wks),1200 gms(0.7kg-1.8kg) & 5 days(3-10days) respectively. Incidence of Septal necrosis was 26.7% in the babies that had ‘No barrier applied at septal hudson prongs interface (Group0), which was significantly more (p<0.001) when compared with other three groups, within which its incidence was 2.8% in Cotton applied at septal and hudson prongs interface with glycerine (Group1), 7.1% in Danaplast applied at interface(Group2) and 0.0% in Cotton soaked with normal saline(Group3) respectively. In Group 0 nasal septal injury Grade 1 is (35%),grade 2 (35%),and grade 3(30.0%), in Group 1, grade 1 septal injury is (84%), grade 2(12.7%) & grade 3(2.8%),In Group 2 grade 1 is (65.7%),grade2(30.0%),grade3 (4.3%) and Group3 grade1(80.7%),grade2(19.3%) and Grade3 (0.0%) Conclusions: Nasal trauma is a frequent complication of NCPAP, especially in preterm babies and babies requiring nasal prongs for longer duration. And can be prevented by applying a barrier as in group 1,2 &3 in our study shows statistically significant decreased in severe nasal septal injury.
Authors and Affiliations
Mushtaq Ahmad Sheikh, Altaf Ahmad Bhat, Rukaya Akhthar, Mudassir Ahad Wani, Tariq Wani
Collection and Transport of Blood
Blood cultures are collected from patients with suspected sepsis or bacteremia and are essential in the diagnosis and treatment of the etiologic agent of septicemia.
Successful Pregnancy After IUI with Retrograde Ejaculated Sperm
Objective: To report a case of successful treatment of complete retrograde ejaculation by superovulation and intrauterine insemination (IUI), by collecting spermatozoa from post-ejaculatory urine. Design: Case report....
Decline in Beta-Cell Function among Adolescents with Type 2 Diabetes Mellitus
It is well known that beta-cell function declines over time in adults with type 2 diabetes mellitus (T2DM). The beta-cell dysfunction, initially characterized by impairment in the first phase of insulin secretion followi...
A Giant Tumour of Breast: Phyllodes Tumour
Phyllodes tumour of breast is a rare fibro-epithelial tumour of the breast accounting for less than 1% of the tumours of breast. They are mostly found in females between 45-49 years of age; in contrast, invasive carcinom...
Laron syndrome – A case Report
Background: Laron & colleagues (1966) reported a rare genetic disorder in Israeli Jewish siblings which was characterized by insensitivity to growth hormone due to an abnormality in the growth hormone receptor or post-re...