CLINICAL EVALUATION OF CLONIDINE AS AN ADJUNCT TO CAUDAL ROPIVACAINE IN PEDIATRIC INFRAUMBILICAL SURGERIES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 37
Abstract
[b]BACKGROUND[/b]: The addition of clonidine as an adjuvant has allowed the use of lower concentration of the local anaesthetic for achieving the same level of anaesthesia but with the prolonged duration of analgesia which increases the margin of safety and reduces the incidence of unwanted motor blockades. With these facts in mind we undertook the study to compare the analgesic properties of 0.25% ropivacaine with the addition of clonidine (1µg/kg) to that of ropivacaine 0.25% following caudal administration in children. [b]METHODS[/b]: After approval from ethical committee 60 children of age 1-10 yrs of ASA grade I or II undergoing elective sub umbilical surgeries were selected for the study. We gave caudal block with 0.25% ropivacaine 1ml/kg+1ml normal saline for group R or 0.25% ropivacaine 1ml/kg + clonidine 1microgram/kg+1ml normal saline to make volume 1ml for group C. To perform caudal block all patient received IV injection glycopyrolate- 0.01mg/kg, IV injection midazolam- 0.1mg/kg and IV Injection ketamine-1mg/kg. Hemodynamic parameters were observed before, during and after the surgical procedure. Quality of surgical anesthesia & requirement of supplemental midazolam/ketamine were also noted. Duration of Post-operative analgesia, pain scores, level of sedation and side effects if any were looked for and duly recorded. [b]RESULT[/b]: Duration of analgesia in group R was 6.45±0.52 hrs. and in group C was 13.01±0.89hrs i.e. significantly prolonged in group C (P<0.0001). Post-operative pain score and sedation score were also significantly better in group C (P<0.0001). The quality of surgical analgesia was also significantly excellent in group C. Other vital parameters were not statistically significant in both the groups.[b] CONCLUSION: [/b]Ropivacaine (0.25%) with clonidine (1μg/kg) in caudal block showed prolong duration of analgesia as well as better quality of surgical anaesthesia than plain ropivacaine (0.25%) in pediatric patients without any significant side effects.
Authors and Affiliations
Urmila Keshari, Sonal Awasya, Tripti Vatsalya
Keywords
Related Articles
- EP ID EP90210
- DOI 10.14260/jemds/2015/933
- Views 94
- Downloads 0
ROLE OF NEEDLE SYNOVIAL BIOPSY IN JOINT DISEASES
Joint disease is a common problem affecting all age groups presenting in orthopedic and rheumatology clinics. Diagnostic difficulties are encountered, particularly, in early stages when radiology and blood...
RIGHT SIDED SIGMOID COLON AND REDUNDANT DESCENDING COLON ON CONVENTIONAL AND CT IMAGING
CASE PRESENTATION A 62-year-old male presented with history of severe constipation, abdominal distension, haemorrhoids and blood in stool in surgical OPD of Guru Nanak Dev Hospital, Amritsar. The patient was referred for...
ROLE OF THORACOLUMBAR INJURY CLASSIFICATION AND SEVERITY SCORE (TLICS) SYSTEM IN DIAGNOSTIC AND PROGNOSTIC EVALUATION OF THORACOLUMBAR SPINAL TRAUMA USING CT AND MRI
BACKGROUND Thoracolumbar spine fractures are common injuries that can result in significant disability, deformity and neurological deficit. A comprehensive classification system is required for classifying thoracolumbar...
EFFICACY OF PERCUTANEOUS CATHETER DRAINAGE IN MANAGEMENT OF LIVER ABSCESSES COMPARED WITH NEEDLE ASPIRATION
BACKGROUND The aim of the study was to evaluate the clinical presentation and to investigate the effectiveness of continuous catheter drainage in comparison to needle aspiration in the treatment of liver absces...
COMPARATIVE STUDY OF INTRA-ARTICULAR HYALURONIC ACID AND INTRA-ARTICULAR TRIAMCINOLONE HEXACETONIDE IN PRIMARY OSTEOARTHRITIS OF KNEE
BACKGROUND Intra-articular (IA) corticosteroid injection has an established therapeutic role, but the effect is short lasting. IA Hyaluronic acid (HA) is considered as a therapeutic alternative in patients who have faile...