SERUM MAGNESIUM LEVELS IN MILD AND SEVERE PREECLAMPSIA AND NORMAL PREGNANT WOMEN
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 21
Abstract
[b] OBJECTIVE[/b]: The aim of this study is to compare serum magnesium levels in women with mild, severe preeclampsia, and normal Pregnant women. [b]MATERIALS AND METHODS:[/b] The present study was conducted in Victoria Government hospital and King George Hospital Visakhapatnam during the period July 2010-June 2011. The study consists of 50 cases of normotensive uncomplicated pregnant women taken as control and 40 cases of mild preeclampsia, 10 cases severe preeclampsia. The samples were collected from the women attending the Antenatal outpatient clinics and from women who were admitted for treatment and delivery. [b]SPECIMEN [/b] [b]COLLECTION:[/b] On admission, venous serum samples were collected when the patients were in the supine position, prior to their commencement to intravenous therapy. The venous blood was taken from the participant’s antecubital vein, placed in a plain vacuum tube. Serum magnesium was measured by colorimetric method by Roche Cobas Integra 800. Other parameters like serum calcium, creatinine, uric acid, fasting blood sugar, and urine sugar and albumin are also measured. The data was analyzed with the SPSS software package version 15.0 and expressed in terms of mean, standard deviation (SD). Continuous variables of serum magnesium concentrations of the three groups were compared by F-test. Maternal and perinatal outcome were analyzed. [b]RESULTS[/b]: The serum magnesium levels in severe preeclamptic women was significantly lower (1.68 + 0.19 mg/dl vs. 2.1 + 0.206 mg/dl, p = 0.0001; and 1.55 + 0.190 mg/dl vs 1.68+0.19mg/dl, p = 0.059. The study of biochemical parameters shows that, the mean serum magnesium levels in control group is 2.10 +/- 0.21, (normal range 1.8-2.4 mg/dl), in mild cases 1.69 +/- 0.19 and in severe cases1.58+/- 0.20. [b]CONCLUSION[/b]: Preeclampsia is more common in primigravida, younger age group and in low socio economic group. Preeclampsia is associated with increased prematurity rate and low birth weight. Preeclampsia is associated with hypocalcaemia, hypomagnesaemia and hyperuricaemia.
Authors and Affiliations
Sujatha R, Madhuri C. H, Sudhamadhuri K. V, Radha T
Keywords
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- EP ID EP101013
- DOI 10.14260/jemds/2015/532
- Views 68
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