3D protein structure prediction of influenza A virus based on optimization genetic algorithm
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2014, Vol 27, Issue 3
Abstract
The 3D structure of close polymer is constituted by the interaction of close contact couples among amino acid residues. In this paper, 3D protein structure of influenza A virus was predicted. Twenty kinds of amino acid residues were divided into four categories according to the number of close contact couples. The stable structure with minimum energy was obtained by using optimization genetic algorithm. The HNXP 3D lattice model was established to predict the 3D protein structure. It can be concluded that the two kinds of structures are significantly similar by computing the similarity.
Authors and Affiliations
Jie Gao , Pei-Xuan Jin , Hong-xing Xu
Bioremediation of petroleum hydrocarbon contaminated soil by Rhodobacter sphaeroides biofertilizer and plants
Bio-augmentation is a promising technique for remediation of polluted soils. This study aimed to evaluate the bio-augmentation effect of Rhodobacter sphaeroides biofertilizer (RBF) on the bioremediation of total pe...
Formulation and evaluation of a single vial lyophilized preparation of technetium-99m labeled ethylene dicysteine as a renal scintigraphic agent
99mTc labeled N-N-ethylene-L, L-dicysteine (EC) was introduced in form of multiple-step kit as an alternate renal imaging radiopharmaceutical for commonly used 99mTc-MAG3. We developed a single component lyophilize...
Effects of total body irradiation on fatty acid and total lipid content of rats
We examined time-dependent changes in plasma lipids of rats given total body irradiation (TBI) with X-rays at 3 Gy. for consecutive periods. Animals were exposed to x ray radiations consecutively for 20 days at 5 day int...
The clinical diagnosis and treatment about 22 cases of limbic encephalitis were retrospectively analyzed
To summarize and analyze the clinical characteristics and treatment of limbic encephalitis, in order to provide the basis for clinical work. We retrospectively analyzed the clinical characteristics, magnetic resona...
Synthesis, characterization and biological activity of some 1, 3, 4-thiadiazol derivatives
Thiadiazoles are their derivatives exhibit a wide variety of pharmacological activities such as Antibacterial and anti-inflammatory. In the present study we have synthesized derivatives some 2,5 substituted 1,3,4- thiadi...