A CASE CONTROL STUDY OF INTRAVENOUS MAGNESIUM SULPHATE IN TREATMENT OF ACUTE ORGANOPHOSPHATE POISONING
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 38
Abstract
BACKGROUND To study the efficacy of intravenous magnesium sulphate in the treatment of OPC poisoning and its outcome. To assess merits and demerits of use of MgSO4 with conventional therapy. METHOD This is a case control study of patients admitted with severe OPC poisoning in intensive care medical unit of tertiary care hospital. RESULTS Total of 69 cases and 64 control patients were compared. Among both cases and controls incidence of poisoning was more common among male sex and common among patients belonging to third decade of age. When compared to control arm, there is statistically significant reduction in mortality when intravenous MgSO4 was given to patients in addition to standard treatment protocol for severe OPC poisoning. CONCLUSION In our study, addition of MgSO4 has shown significant clinical improvement of severe OPC poisoning with no adverse outcome. Long term and large studies are needed to determine the efficacy of MgSO4 in treatment of OPC poisoning.
Authors and Affiliations
James , Vajaravelu , Parthasarathy
Keywords
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- EP ID EP90895
- DOI 10.14260/jemds/2016/532
- Views 82
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