A COMPARATIVE STUDY OF EFFECT OF 0.5% AND 0.75% ISOBARIC ROPIVACAINE IN SPINAL ANAESTHESIA IN PATIENTS UNDERGOING ELECTIVE LOWER LIMB SURGERIES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 30
Abstract
OBJECTIVES The study was conducted to compare the differences in the onset, duration of action and complications of intrathecal isobaric ropivacaine 0.5% (Group I) and intrathecal isobaric ropivacaine 0.75% (Group II) in elective lower limb surgeries. METHODS We enrolled 60 patients of ASA (American Society of Anaesthesiologists) Grade I-II scheduled for lower limb surgeries under spinal anaesthesia for this prospective randomized control trial. The patients were randomized to receive either 15 mg of 0.5% isobaric ropivacaine or 22.5 mg of 0.75% isobaric ropivacaine intrathecally. The time of onset of sensory and motor block, haemodynamic status, time for regression of sensory level to T10 dermatome, time of first request of analgesics and adverse effects were compared in both the groups. RESULTS The time of onset of sensory and motor block was significantly longer in Group-I than Group-II (P<0.001). Haemodynamic changes did not differ in patients of either group (P>0.05). The onset of analgesia was faster in Group II (2.13±0.50 mins.) than Group I (2.6±0.93 mins.). The time for regression of sensory level to T10 dermatome (Group-I 150±28.9 minutes and Group-II 180±32.07) were statistically longer in Group II (P<0.001). The time of first request of analgesics by the patient in Group-I was 197±31.20 minutes and in Group II was 219±31.66 minutes, which was statistically significant (P<0.001). The onset of motor block was quicker (P˂0.05) and the total duration of motor block was longer (P˂0.05) in Group II. No unexpected adverse events were registered. CONCLUSION The subarachnoid injection of glucose-free isobaric ropivacaine 0.5% and 0.75% solutions results in a variable spread of analgesia, accompanied by a good quality of motor block. Ropivacaine 0.75% produces a better quality of analgesia and longer duration of analgesia than the 0.5% solution.
Authors and Affiliations
Tridip Borah, Anulekha , Dipika
Keywords
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- EP ID EP133669
- DOI 10.14260/jemds/2016/363
- Views 84
- Downloads 0
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