A comparison among three different analytical methods to test the scavenging properties of different integrators against radicalic stress
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2014, Vol 27, Issue 1
Abstract
The aim of the present work was to experimentally evaluate the total antioxidant capacity of different commercially available pharmaceutical integrators based on vitamin E, astaxanthin, resveratrol and blueberry using the traditional DMPD-FeCl3 spectrophotometric method and the ORAC spectrofluorimetric method, largely discussed and described in literature and considered as reference methods. The results were compared with those ones obtained with a biosensor based on superoxide dismutase (SOD) enzyme. Precision of antioxidant capacity measures for all integrators was good, generally with a R.S.D.% £10% for all methods employed. An evaluation was also performed of the possible influence on the total integrator antioxidant capacity from other compounds and/or excipients present in the formulations which can interfere with the main antioxidant component of the commercial integrator
Authors and Affiliations
Riccarda Antiochia , Tania Gatta , Elisa Mazzone , Luisa Mannina1 , Luigi Campanella
Keywords
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