A HISTOMORPHOLOGICAL STUDY OF PAEDIATRIC ADRENAL TUMOURS

Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 22

Abstract

 BACKGROUND: Tumors of the adrenal gland are extremely rare in children. Those of the adrenal cortex account for only 0.3-0.4 % of all childhood neoplasms. Its rarity has hindered the identification of meaningful prognostic factors. Because very few children have been treated for adrenal tumors, even at major cancer centers, clinical experience is relatively limited and optimal therapy has not been established. Even though assessment of malignancy through histological criteria has been controversial, several investigators reported high degree of accuracy in the evaluation of malignancy by microscopic examination(1, 2). Furthermore, Bugg et al reported that histological type and tumour weight were the most reliable predictors of tumour behaviour in the paediatric age group. AIM: To analyze various adrenal tumors based on histopathological pattern and correlate with clinical findings. [b]MATERIALS AND METHODS[/b]: The study included 12 surgical specimens of adrenal gland out of which 3 were resected and 9 were biopsied specimens, collected between JULY 2006 to JUNE 2011 at Institute of Child Health, Niloufer hospital , Hyderabad. Tissues were processed and histopathological patterns were studied on Hematoxylin and Eosin stained sections. Immuno histochemistry was done in relevant cases and the markers used were Ki-67, Synaptophysin, NSE, Chromogranin. [b]RESULT[/b]: The study showed incidence of 75% in male and 25% in female children with predilection towards left adrenal gland.

Authors and Affiliations

Ramani M, Radhika Krishna, Geetha K, Ramesh Reddy, Sreenivas Reddy, Chandu Revathi, Ibraheem Javeed, Puja Deshmukh

Keywords

Related Articles

A RARE CASE REPORT OF ASYMPTOMATIC SEVERE PRIMARY PULMONARY HYPERTENSION IN PREGNANCY

PRESENTATION OF CASE Patient, Mrs. X, first presented to us in OPD as primigravida in her seventh month of pregnancy after being referred by a private practitioner. She had no complaints apart from occasional palpitation...

HYALINISING TRABECULAR TUMOUR OF THE THYROID GLAND– A DIAGNOSTIC CHALLENGE

A 42-year-old housewife presented to the Otorhinolaryngology Outpatient Department with a painless swelling of left side of the neck, insidious in onset, gradually increasing in size since 1 year. On local examination, t...

TREATMENT OF JUXTA-ARTICULAR GIANT CELL TUMOURS WITH CUSTOM MADE MEGAPROSTHESIS

BACKGROUND Juxta-articular giant cell tumours are common and pose a special problem of reconstruction after tumour excision. This article analyses the functional outcome after resection of juxta-articular giant cell tumo...

A PROSPECTIVE TRIAL COMPARING THE ACCURACY BETWEEN ULTRASOUND GUIDED FNAC OF AXILLARY LYMPH NODES AND SENTINEL LYMPH NODE BIOPSY USING METHYLENE BLUE FOLLOWED BY IMPRINT CYTOLOGY IN CLINICALLY NODE NEGATIVE EARLY BREAST CANCERS

BACKGROUND Surgical treatment of breast cancer has evolved from Halsted’s radical mastectomy to breast conserving surgery. Similarly, surgical treatment of regional lymph nodes has also become less extensive. Axillary ly...

 BILATERAL THALAMIC HAEMORRHAGE FOLLOWING BURR HOLE DRAINAGE OF CHRONIC SUBDURAL HEMATOMA

 Bilateral thalamic haemorrhage is an unusual complication of burr hole drainage surgery. We present the case of a patient with this rare postoperative complication of bilateral thalamic haemorrhage following burr...

Download PDF file
  • EP ID EP95579
  • DOI 10.14260/jemds/772
  • Views 99
  • Downloads 0

How To Cite

Ramani M, Radhika Krishna, Geetha K, Ramesh Reddy, Sreenivas Reddy, Chandu Revathi, Ibraheem Javeed, Puja Deshmukh (2013).  A HISTOMORPHOLOGICAL STUDY OF PAEDIATRIC ADRENAL TUMOURS. Journal of Evolution of Medical and Dental Sciences, 2(22), 3849-3856. https://europub.co.uk/articles/-A-95579