ANTIBIOTIC RESISTANCE IN CSOM IN A TEACHING HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 61
Abstract
BACKGROUND Antibiotic resistance pattern of CSOM has been changing according to geographical variation and differences in patient population. Increased and irrational use of broad spectrum antibiotics, as well as resistance in bacterial isolates, has become very common. Staphylococcus is one of the most important bacteria in CSOM and MRSA is a common pathogen in otologic diseases. Continuous and periodic surveillance of MRSA is necessary to reduce the spread of antibiotic resistant pathogens in CSOM cases. OBJECTIVES To identify the bacteria causing CSOM, to determine the antibiotic resistance of the isolates from CSOM samples and also to determine the methicillin resistance of the isolates. MATERIALS AND METHODS Prospective study of 30 samples from clinically suspected cases of CSOM was performed over a period of two months. Samples were processed by microscopy and culture and the culture isolates were identified by standard biochemical reactions. Antibiotic susceptibility test of the isolates was performed as per CLSI guidelines. RESULTS 73.33% of the isolates were Staphylococcus aureus. 26.66% of the isolates were Enterococcus. 100% resistance to Cotrimoxazole, Ampicillin sulbactam, Azithromycin, Cefuroxime, Cefazolin, Doxycycline, Tetracycline and Cefepime was observed followed by 50% resistance to Amikacin and 43.3% resistance to Amoxiclav and Ceftazidime. MRSA constituted 50% of the total isolates. CONCLUSION Cotrimoxazole, Ampicillin sulbactam, Azithromycin, Cefuroxime, Cefazolin, Doxycycline, Tetracycline and Cefepime should not be considered for treatment of CSOM in our hospital area. There is an over use of Cefepime and Ceftazidime in our hospital area. Increased isolation of MRSA warrants potential interventions to reduce the prevalence of MRSA in our hospital area.
Authors and Affiliations
Rangaineni Sena, Gandham
Keywords
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- EP ID EP96419
- DOI 10.14260/jemds/2016/973
- Views 103
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