Antimicrobial potentials of different solvent extracted samples from Physalis ixocarpa
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2016, Vol 29, Issue 2
Abstract
The present study investigates the antimicrobial activities of different solvent extracted samples isolated from different parts of Physalis ixocarpa through disc diffusion assay using three different concentrations. Statistical analysis of the data revealed that different parts of the plant showed varying degree of inhibition against different bacteria at different concentrations. Different solvent extracted samples from the calyx showed inhibitory activity against most of the bacteria under study. Extracts from leaf and fruit samples showed activity against S. aureus and K. pneumoniae and extracts from the stem tissues were effective to control the growth of E. coli and K. pneumoniae. Crude methanolic extract from the stem and n-butanol extracted samples from fruit exhibited strong inhibitory activity against Klebsiella pneumoniae at highest concentrations. Antifungal activity was observed only in crude methanol extract from the leaf against Rhizopus stolinifer, Aspergillus niger and Penicillium chrysogenum.
Authors and Affiliations
Wajid Khan , Jehan Bakht , Mohammad Shafi
Keywords
Related Articles
- EP ID EP128346
- DOI -
- Views 104
- Downloads 0
In vitro antimicrobial, antioxidant activity and phytochemical screening of Apium graveolens
The present study evaluates the phytochemical screenings, antioxidant activity and antimicrobial assay of Apium graveolens L. The phytochemical screening showed the presence of flavonoids, tannins, saponins and ste...
Efficacy of combination herbal product (Curcuma longa and Eugenia jambolana) used for diabetes mellitus
The purpose of this research was to evaluate the efficacy of a combination herbal product that is traditionally used for managing diabetes mellitus. Herbal drug contains Curcuma longa and Eugenia jambolanain the ra...
Honey bee is a potential antioxidant against cyclophosphamide-induced genotoxicity in albino male mice
The protective effects of honey bee (HB) and pollen grains against cyclophosphamide (CPM) -induced cytotoxic and genotoxic effects in mice were investigated. This was achieved through study the effects of CPM and...
The surface protease OmpT serves as Escherichia coli K1 adhesin in binding to human brain micro vascular endothelial cells
Escherichia coli (E. coli) K1 is the most common bacteria that cause meningitis in the neonatal period. But it’s not entirely clear about how E. coli crosses the blood-brain barrier. The features of the OmpT deleti...
The preparation of the sustained release metformin hydrochloride microcapsules by the Wurster fluidized bed
The main objective of this study was to prepare sustained release metformin hydrochloride microcapsules by the Wurster fluidized bed and to obtain the optimized coating process and formulation. Fine microcapsules w...