Antioxidant And Cytotoxic Activities Of Crude Methanolic Extract Of Medicago Polymorpha
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2013, Vol 3, Issue 8
Abstract
Free radicals are the source of many diseases such as diabetes mellitus, cancer, arthritis, anemea, Parkinson disease, alzimer and ageing etc. Antioxidants are very important for treatment of this disease by scavenging free radicals. The present study was conducted to determine the Cytotoxic and antioxidant activities of metanolic extract of Medicago polymorpha against free radicals such as DPPH and ABTS etc in vitro. These activities of Medicago polymorpha are count for its anticancer properties. The results were analyzed by the comparison of the extract with the standards. Ascorbic acid was used as a standard for antioxidants assays and see salt solution without extract was used a standard for cytotoxic assays. The antioxidant property may be related to the polyphenols and flavonoids present in the extract. These results clearly indicate that Medicago polymorpha is effective against free radical mediated disease and thus it has potential for treating cancer.
Authors and Affiliations
Muhammad Khan, Syed Waqas, Suhaib Asad
Keywords
Related Articles
- EP ID EP109761
- DOI -
- Views 112
- Downloads 0
Novel RP-HPLC Method for Simultanious Determination of Sitagliptin and Simvastation in Bulk and Tablet Dosage Form
A simple, rapid, accurate, precise and novel high-performance liquid chromatographic method for simultaneous analysis of Sitagliptin (SITA) and Simvastation (SIMV) in pharmaceutical dosage form has been devel...
‘To Study the solid waste generated per bed per day at district hospital kargil a remote high altitude area
Objective: 1) To study the solid waste generated per bed per day at District hospital Kargil. 2) To study the existing system of solid waste segregation, collection, transport, storage and disposal at District ho...
Evaluation of phytochemistry and uterotonic activity of root aqueous extract of Uvariodendron anisatum verdec. used in childbirth in Eastern/Central Kenya.
Over 56 % of pregnant women in Kenya deliver at home with the assistance of mainly traditional birth attendants who use herbal remedies to complete the processes of child bearing in both urban and rural communit...
Determination of concentration intra-erythrocyte of metformin in type 2 diabetic patients with or without renal impairment : Comparative study of concentrations intra-erythrocytes between two groups of diabetic patients
ABSTRACT : Type 2 diabetes and renal failure are insidious diseases. Worldwide, diabetes is the leading cause of chronic kidney disease. In Morocco, diabetes and kidney disease are two diseases on the rise and...
Asymptomatic Bacteriuria among Pregnant Women Attending Antenatal: Evaluation of Screening Test
Introduction: Asymptomatic bacteriuria in pregnancy is common with a prevalence of 2 – 10% and is similar tothat observed among non–pregnant women. It is however more likely to progress to symptomatic urinary tract...