Blood group distribution and its relationship with bleeding time and clotting time
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2015, Vol 5, Issue 3
Abstract
Background: Blood group plays a vital role in the field of transfusion medicine. The relationship between bleeding time, clotting time, and blood group is important in certain clinical conditions such as epistaxis, surgery, and thrombosis. Researchers have shown that epistaxis is more often encountered in patients having blood group O probably due to lower expression of von Willebrand factor, and elevated levels are a risk factor for thrombosis. Thus, earlier studies found prolonged bleeding and clotting time in individuals with O blood group. Aims and Objectives: The objective of the study was to assess the relationship between bleeding time and clotting time among various blood groups and to identify any gender difference among the same. Materials and Methods: Our study included 150 MBBS students in the age group of 17–20 years. The blood grouping was carried out with the standard antisera, and bleeding time and clotting time were estimated by Duke method and capillary tube method respectively. Finally, bleeding time and clotting time of different blood groups were compared and statistical analysis was carried out. Results: Blood group B (40.7%) was the most common blood group in both genders followed by O (27.3%), A (20.7%), and AB (11.3%). Bleeding time was found to be prolonged 44 min in maximum number of group O (22%) followed by group B (18%), group AB (5.9%), and group A (3.2%) but the difference was statistically insignificant (p = 0.509). Similarly clotting time was 46 min in group B (14.8%) followed by group O (14.6%), group AB (11.76%), and group A (9.7%) but the difference was statistically insignificant (p = 0.885). Gender-wise bleeding time was more prolonged in females (15.7%) than males (13.1%) but the difference was statistically insignificant (p = 0.236), similarly clotting time too was prolonged more in females (16.9%) than males (9.8%) but again the difference was statistically insignificant (p = 0.662). Conclusions: In our study, blood group B predominated followed by O, A, and AB. Bleeding time was prolonged 44 min in blood group O followed by B, AB, and A whereas clotting time was prolonged 46 min in blood group B followed by O, AB, and A. Gender-wise bleeding and clotting time were higher in females than males.
Authors and Affiliations
Manjeet Kaur, Arvinder Singh, Roopam Bassi, Deepinder Kaur
Keywords
Related Articles
- EP ID EP149226
- DOI 10.5455/njppp.2015.5.2609201433
- Views 65
- Downloads 0
Relation between sleep quality and circulatory levels of inflammatory marker in women of reproductive age group
Background: Alteration in hormonal environment during various phases of a woman’s life contributes sleep disturbances in women. Poor sleep alters the immune system through centrally produced cytokines which is a cause of...
Comparison of case-based learning and traditional lectures in physiology among first year undergraduate medical students
Background: Physiology is basic and applied medical science. The traditional system of teaching in physiology is teacher cantered with minimal participation from the students. Case-based learning (CBL) is a self-directed...
Microbiological and clinical response of superoxidized solution versus povidone iodine in the management of lower limb ulcers
Background: Lower limb ulcers are debilitating and associated with significant morbidity, loss of productivity and decreased the quality of life. Currently used antiseptics are cytotoxic, damage the granulation tissue an...
Effect of Ujjayi Pranayama on cardiovascular autonomic function tests
Background: Life, nowadays, is full of stress, and stress become almost an integral part of our daily routine life. It affects the every aspect of our life and leads to development of stress-related disorders such as hyp...
Evaluation of hypolipidemic effect of stem part of Berberis aristata in Type 2 diabetes mellitus patients as add on therapy
Background: Diabetes mellitus (DM) is one of the oldest common metabolic disorders characterized by hyperglycemia, hyperlipidemia, negative nitrogen balance, and ketonemia. It is a one of the most important pathological...