CHANGING BACTERIAL ORGANISMS AND ANTIMICROBIAL RESISTANCE PATTERN AMONG HOSPITALIZED COMMUNITY ACQUIRED PNEUMONIA PATIENTS IN A TERTIARY CARE CENTER
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 13
Abstract
[b] BACKGROUND[/b]: Most of the times a Community Acquired Pneumonia (CAP) patient is being treated with empirical antibiotics by best guess method by the clinician.MDR strains are being reported from c/s reports and Gram negative rods are fast increasing both in the etiology and mortality of CAP patients. [b]AIM OF STUDY[/b]: 1. To find out the profile of different bacteria causing CAP at a tertiary hospital. 2. To know the treatment outcome & drug resistance pattern among culture positive CAP patients. [b]MATERIALS & METHODS[/b]: 450 CAP patients admitted & treated between Jan. to Dec.2012 at Victoria Hospital, Bangalore were included in this hospitalized cross sectional study. All relevant investigations including sputum c/s were done. [b]RESULTS[/b]: Positive culture reports were obtained in 165(36.33%) out of 450 patients Following are the isolates-Strept.pnemoniae 32.7%, Klebsiella 18.2%, Staph.aureas 10.9%, Psedomonas 10.9%, E.coli 5.4%, Acinetobacter 7.3%, H.influenza 5.4%, Mixed growth 10%. 76% of patients recovered from CAP, 6% went against medical advice, 6.6% showed unresolved pneumonia & deaths in 5.33% of patients. High degree of resistance was noted to many antibiotics including to latest cephalosporins. [b]CONCLUSION[/b]: This study highlights the importance of culture tests and selection of proper antibiotics and to avoid misuse & abuse of higher antibiotics to prevent the emergence of MDR strains. An antibiotic policy at every level may help.
Authors and Affiliations
Raveendra Ramamurthy, Ravi Ningappa, Jayachandra
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