CLINICAL PROFILE OF HEPATITIS B VIRUS INFECTION IN PATIENTS ATTENDING TERTIARY CARE CENTRE IN EASTERN INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 37
Abstract
AIMS A cross-sectional Study, performed in two tertiary care referral clinics to determine the clinical profile of Hepatitis B patients attending tertiary care centres in Eastern India. Patients were segregated as symptomatic and asymptomatic. RESULTS The age of the patients varied from 16-76 years. The mean age of the patients was found to be 34.54 years with a standard deviation of 13.53 years. Only 16% of the patients were symptomatic on presentation. Common clinical features were nausea (22%), splenomegaly (22%), jaundice (13%), abdominal pain (19%) and hepatomegaly (10%). Bilirubin and alanine transaminase (ALT) levels were significantly higher in symptomatic patients. Strong significant positive correlation found between AST and Bilirubin (r=0.346), p value=0.0004; ALT and Bilirubin are positively correlated (r=0.298), p value=0.003; ALT and AST are positively correlated(r=0.710), p value=<0.0001; ALT and Albumin are positively correlated(r=0.216), p value=0.031(Moderate significant correlation) in the entire study population. CONCLUSION The current study demonstrates the clinical and biochemical features that a hepatitis B infected patient may present with. Most of the patients with hepatitis B are asymptomatic (84%) on presentation. To our knowledge, this is the first paper reported from Eastern India in recent times which has shed a light on the differences in the pattern of the biochemical parameters among the symptomatic and asymptomatic hepatitis B infected patients.
Authors and Affiliations
Champa , Sekhar , Kingshuk
Keywords
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- EP ID EP128564
- DOI 10.14260/jemds/2016/518
- Views 93
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