CLINICAL STUDY OF MELASMA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 26
Abstract
[b]OBJECTIVES[/b]: 1) To know the incidence of melasma in both men and women. 2) To know the clinical types 3) To assess the efficacy of various modalities of treatment of melasma. [b]MATERIALS AND METHODS[/b]: A prospective study was conducted from 1.12.2006 to 30.11.2008 in C.G hospital and Bapuji hospitals attached to J.J.M.M College Davangere. The study was approved by the ethical committee of our hospital. 200 patients were studied and a detailed history was taken after taking consent from the patients the following regimens was followed. Regime IA: Pre peeling with retinoic acid, hydroquinone and steroid cream + Glycolic acid peeling Regime IB: Pre peeling with retinoic acid, hydroquinone and steroid cream + Trichloro acetic acid Regime IIA: Sunscreens + hydroquinone Regime II B: Hydroquinone only Regime III: Sunscreens + Azelaic acid, Regime IV: Sunscreens + Hydroquinone + retinoic acid + fluorinated steroid. [b]RESULTS[/b]: Females were most commonly affected and use of cosmetic was the common aggravating factor. The malar type was the most common presentation and regarding treatment regimen IA and B was the most effective. Regarding the response to treatment there was a significant improvement in Patients who were given pre peeling with Hydroquinone and Retinoic acid cream Followed by chemical peeling with Trichloroacetic acid a Glycolic acid. In patients treated with fluorinated steroid + retinoic acid + hydroquinone there was also a considerable improvement. Compared to the above 2 regimens, in patients treated with Hydroquinone and azelaic acid cream, there was no much improvement.
Authors and Affiliations
Lingaraj M. M, Vijayakumar M. ,M, Nadiga Rajashekar
Keywords
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