Comparative study of serum lipid levels in normotensive and pre-eclamptic Nigerian women
Journal Title: International Journal of Medicine and Biomedical Research - Year 2014, Vol 3, Issue 2
Abstract
Background: Pre-eclampsia is a common syndrome that occurs in the second half of pregnancy and often manifest with hypertension and significant proteinuria. It occurs in up to 10% of pregnancies and is the second cause of maternal mortality worldwide accounting for 17% of maternal deaths in Nigeria. Aim: This study was performed to compare the serum lipid levels of pregnant normotensive and pre-eclamptic women. Methods: It was a case control study involving 50 normotensive and 50 pre-eclamptic women at the University College Hospital, Ibadan, making a total of 100 participants. Their venous blood (5mls) was collected after an overnight fast of 8-12 hours and this was analysed for cholesterol, triglyceride, high density lipoprotein-cholesterol (HDL-C), very low density lipoprotein-cholesterol (VLDL-C) and low density lipoprotein-cholesterol (LDL-C) using standard enzymatic methods. Results: The study showed that there was a significantly higher levels of triglyceride, VLDL-C and HDL-C in the pre-eclamptic compared to the normotensive group (P<0.05). Also on Spearman´s Correlation, there was a significant positive correlation between these lipids and pre-eclampsia. Conclusion: Lipids therefore have an important role in the aetiopathogenesis of pre-eclampsia and could be estimated during the conservative management of patients with pre-eclampsia.
Authors and Affiliations
Irinyenikan T. A , Arowojolu A , Olayemi O
Keywords
Related Articles
- EP ID EP106922
- DOI 10.14194/ijmbr.3.2.10
- Views 116
- Downloads 0
A 5 year review of pregnancy outcome and interval to delivery after cervical cerclage in north-eastern Nigeria
Background: Evidences have shown the value of cerclage in reducing preterm birth in women with cervical incompetence. Aim: To document the pregnancy outcome in women with cervical incompetence after cerclage insertion an...
Clozapine-induced atypical neuroleptic malignant syndrome
No abstract for this article
Quality and safety evaluation of a Ghanaian polyherbal product EAF-2011 for the management of superficial mycoses
Background: The widespread use of herbal medicines in recent years means that issues concerning their quality, safety and efficacy need to be answered. In the current study, the polyherbal formulation EAF-2011 used in th...
Knowledge and attitude of nurses to Community Psychiatry services in Edo state, Nigeria.
Background: Community Psychiatry involves support and treatment of people with mental disorder in a domiciliary setting instead of mental hospital. The attitude of the public towards mental illness and mentally ill...
Preface to the 2nd issue of the International Journal of Medicine and Biomedical Research, 2013