COMPARATIVE STUDY OF THE EFFICACY OF MIFEPRISTONE WITH VAGINAL MISOPROSTOL AND VAGINAL MISOPROSTOL ALONE FOR FIRST TRIMESTER ABORTION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 63
Abstract
OBJECTIVES To assess the efficacy of mifepristone with misoprostol combination in first trimester abortion. To compare this combination with vaginal misoprostol alone for the first trimester MTP. To compare the various parameters involved in MTP in both the methods and assess the most suitable method for first trimester MTP. METHODS An interventional prospective study conducted in the Department of Obstetrics and Gynaecology at Government Thoothukudi Medical College, Thoothukudi, during 2013-2015. During this study, 125 patients who attended the family planning clinic requesting first trimester termination of pregnancy were selected based on the inclusion, exclusion criteria. Out of 125 patients, 100 were randomly assigned to vaginal misoprostol group and 25 to mifepristone with misoprostol group. The study was approved by the hospital ethical committee. RESULTS On analysing both the methods had less induction abortion interval, but 93% of abortions occurred within 4 hours of administration in mifepristone and vaginal misoprostol. CONCLUSION Thus, the combined regimen has more rate of complete abortion with less induction abortion interval than when misoprostol alone was used.
Authors and Affiliations
Hemalatha Raj, Subburathinam
Keywords
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- EP ID EP133801
- DOI 10.14260/jemds/2016/1020
- Views 103
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