COMPARISON OF HAEMODYNAMIC PROFILE AFTER SPINAL ANAESTHESIA IN PATIENTS ON REGULAR TREATMENT WITH CALCIUM CHANNEL BLOCKERS AND β BLOCKERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 34
Abstract
BACKGROUND Hypertensive patients develop wide swings in blood pressure intraoperatively, especially after spinal anaesthesia. Long term antihypertensive agents can modify this effect by controlling blood pressure. This study was undertaken to evaluate the haemodynamic effect in hypertensive patients on regular treatment with calcium channel blockers and beta-blockers who are undergoing elective surgery under spinal anaesthesia and compared with normotensives. AIMS To study the intraoperative changes of blood pressure and heart rate in patients on calcium channel blockers and beta-blockers undergoing surgery under spinal anaesthesia and to compare the data with normotensive patients. MATERIALS AND METHODS 90 patients were included in the study; 30 patients were normotensives (Group N) and 30 patients were hypertensives who were regularly on calcium channel blockers (Group C) and 30 patients on beta-blockers (Group B). Both the groups continued the drug on the day of surgery. The baseline blood pressure and heart rate were recorded. After spinal anaesthesia, the blood pressure and heart rate were noted at 2 min, 4 min, 6 min, 8 min, 10 min, 15 min and thereafter with 5 minutes interval till the end of the procedure. STATISTICAL ANALYSIS Baseline data was analysed using descriptive statistics. Intragroup variation in parameters analysed by one way ANOVA and within the different time intervals by post-hoc test. Intergroup comparison by unpaired ‘T’ test. P value <0.05 considered statistically significant. RESULTS The hypotension was evident in Group C compared to other groups, but bradycardia (heart rate <60) more seen in Group B and were statistically significant (P<0.001). The usage of rescue medication was more in study group and was statistically significant (P<0.002). CONCLUSION Incidence of hypotension was more with patients on calcium channel blockers and required vasopressors and fluids, but incidence of bradycardia was seen more in patients on beta blockers who needed atropine. Anaesthesiologists should anticipate and be adequately prepared for any untoward consequences.
Authors and Affiliations
Kavyashree , Muralidhara Patel, Girish , Ravishankar
Keywords
Related Articles
- EP ID EP101737
- DOI 10.14260/jemds/2016/455
- Views 129
- Downloads 0
A NON-RANDOMISED, COMPARATIVE CROSS-SECTIONAL STUDY TO ANALYSE THE SIGNIFICANCE OF ‘PRESSURE-TO-CORNEA INDEX’ IN PSEUDOEXFOLIATION EYES WITH AND WITHOUT CLINICAL GLAUCOMA
BACKGROUND Pseudoexfoliation syndrome is an age-related systemic disease manifesting itself primarily in the eyes and is characterised by the accumulation of microscopic granular amyloid-like protein fibres. Pseudoexfoli...
QUALITY OF LIFE AND ITS RELATIONSHIP TO SEVERITY OF ADDICTION- A CROSS SECTIONAL HOSPITAL-BASED STUDY AMONG ALCOHOL DEPENDENT PATIENTS
BACKGROUND WHO has estimated that alcohol accounts for 4% of all disease burden worldwide. Alcohol is the 3rd leading cause of disability in the developed world. It causes 5.9% of all deaths globally & 5.1% of the disabi...
CLINICAL EFFICACY OF TACROLIMUS IN INFANTILE HAEMANGIOMA
BACKGROUND Infantile haemangiomas (IH) are the most common benign vascular tumours in childhood and occur in up to 10% of infants. Majority of IHs are apparent by the first month of life, rapidly grow till 5 months of ag...
ONLAY MESH REPAIR OF INCISIONAL HERNIA IS EFFECTIVE WITH LOW RECURRENCE AND COMPLICATIONS
BACKGROUND Incisional hernia after abdominal surgery is a well-known complication. Controversy still exists with respect to the choice of hernia repair technique. Aims and Objectives- To study the complications and recur...
OESOPHAGEAL PERFORATION SECONDARY TO LEMON IMPACTION AND TWO OTHER CASES- A RARE CASE REPORT
We came across a case of 50 years old female with complaints of dysphagia and loss of appetite since 15 days. Flexible and rigid endoscopy was done along with HRCT Thorax, wherein foreign body was identified in lower 2/3...