CORRELATION BETWEEN SEVERITY OF ALCOHOL DEPENDENCE WITH AGE OF ONSET AND FAMILY HISTORY AMONG URBAN ALCOHOLICS: A CROSS-SECTIONAL STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 52
Abstract
BACKGROUND A potentially powerful predictor of progression to alcohol-related harm is age at first use. Evidence suggests that the earlier the age at which young people take their first drink of alcohol, the greater the risk of abusive consumption and the development of alcohol related disorders. Equally important is the family history of alcoholism, which is associated with early age of drinking. AIM This study specifically aims to explore the relationship between severity of alcohol dependence with family history of alcoholism and age of onset of alcohol use. MATERIALS AND METHODS For a period of six months, we conducted a cross sectional study among 200 male subjects aged between 20–50 years who reported the alcohol and drug dependence clinic of a tertiary care hospital in Chennai, Tamilnadu State with problem drinking in the past one year. We used Alcohol Use Disorder Identification Test (AUDIT), Clinical Institute Withdrawal Assessment for Alcohol (CIWA-AD), Severity of Alcohol Dependence Questionnaire (SADQ), Family History Method, and Schedule for Clinical Assessment in Neuropsychiatry (SCAN) for assessment. 123 subjects were Family History Positive (FHP) and 77 were family history negative (FHN). The data was analysed using a computerized Statistical Software programme (SPSS version 20.0 for windows). Descriptive statistics was used to describe the socio-demographic variables. Student t-test was used to compare between ordinal groups. Pearson’s correlation was used for assessing the correlation between the variables. RESULTS The mean severity scores were significantly different between the early age of onset and late age of onset groups. The mean current age in the FHP was 38.61±8.59 and 42.12±6.90 in FHN. The Mean AOO in the FHP was 22.89±4.61 and in the FHN was 26.51±26.51 and was significantly different from each other (P<0.000). The Mean SADQ score were 44.59±10.79 in FHP and 38.96±11.50 in the FHN. This was also significantly different between the two groups (P<0.001). CONCLUSION The two key findings of this study are that alcoholism severity is related to family history of alcoholism and also age of onset of alcoholism independent of each other.
Authors and Affiliations
Harihara , Alexande James, Arunkumar
Consulting Physician, Department of Medicine, AKJ Healthcare and Diagnostics, Saharanpur, Uttar Pradesh, India.
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