CURRENT TRENDS IN MICROBIAL PROFILE AND RESISTANCE PATTERN IN CSOM IN A SEMIURBAN HOSPITAL OF SOUTHERN INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 34
Abstract
BACKGROUND Infections of the middle ear space and their sequelae have plagued mankind from the beginning of time. Since there are variations in aetiological agents and their antimicrobial susceptibility patterns regionally. It is pertinent to carry out ongoing studies to observe the profile of aetiological agents and their resistance patterns. This would help clinicians to prescribe appropriate and effective antibiotics and prevent emergence of Multi-Drug Resistant (MDR) bacteria. AIM To study the spectrum of aerobic bacterial and fungal aetiological agents among patients clinically diagnosed as CSOM. METHODS AND MATERIAL This study was conducted on 105 patients of clinically diagnosed cases of CSOM attending ENT OPD of a semi-urban tertiary care level hospital. After proper sample collection by sterile aural swabs, they were immediately sent to the microbiology laboratory for aerobic bacterial and fungal culture, isolation and identification. Routine antibacterial susceptibility and detection of MRSA and ESBL was carried as per CLSI guidelines. RESULTS AND CONCLUSION The commonest age group affected was 10 months - 10 years (30/28.5%), mainly affecting males (59.4%). Patients were mainly from rural background (81.91%) and majority of cases were reported in the months of May to August. Out of 105 patients, Gram negative isolates were 54 (51.4%) and Gram positive isolates were 34 (32.4%), 10 (9.5%) were fungal isolates and remaining 12 (11.4%) showed no growth. P. aeruginosa (34.3%) was the predominant bacterial organism isolated followed by Staphylococcus aureus (28.6%). Out of 30 isolates of S. aureus, 10 (33.3%) were MRSA and out of 18 Gram negative isolates, 6 (33.3%) were ESBL producers. Antibiogram of all isolates revealed that Amikacin was the most sensitive drug amongst all gram positive and gram negative organisms. Imipenem was the most sensitive drug among gram negative isolates, whereas Vancomycin was the most sensitive drug among gram positive isolates.
Authors and Affiliations
Upasana , Pratima , Dinesh Mathur, Gyaneshwari
Keywords
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- EP ID EP144108
- DOI 10.14260/jemds/2016/454
- Views 88
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