Cyclic fluctuation of bleeding time and clotting time in various phases of menstrual cycle
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2015, Vol 5, Issue 4
Abstract
Background: The physiologic mechanisms whereby the human endometrium maintains hemostasis during endovascular trophoblast invasion, yet permits menstrual hemorrhage, are unknown. Aims and Objective: To find out whether hemostatic responses alter during various phases of normal menstruation. Materials and Methods: In this study height, weight, body mass index, pulse, and blood pressure were measured in 60 female volunteers having normal, regular menstrual cycle. Bleeding and clotting time were measured during three phases of single menstrual cycle: menstrual, follicular, and luteal. One-way analysis of variance test with Bonferroni correction was used to find out statistical significance. Results: This study shows mean bleeding time at follicular phase was significantly (P o 0.05) less as compared to that at menstrual and luteal phases. Mean clotting time at follicular phase was comparatively less than that at menstrual and luteal phases, but the difference was not significant (P 4 0.05). Conclusion: Our observations indicate that primary and secondary hemostatic mechanism activities are at their high in the follicular phase than in the luteal and menstrual phases
Authors and Affiliations
Yogita D Sulaxane, Sharad G Patel
Keywords
Related Articles
- EP ID EP96193
- DOI 10.5455/njppp.2015.5.3001201536
- Views 91
- Downloads 0
Peak expiratory flow rate in healthy school children
Background: Peak expiratory flow rate (PEFR) assesses the overall functional status of the respiratory system. Aims and Objectives: The aim of this study was to observe the PEFR in school going healthy children, in a tow...
Antibacterial activity test of dayak onions (Eleutherine palmifolia L. Merr.) ethanolic extract against Shigella dysenteriae ATCC 13313
Background: Acute bloody diarrhea, which is also called dysentery, is damaged of the intestinal mucosa, sepsis, and malnutrition. Shigella bacteria cause 50% of cases of dysentery; it is due to its ability to produce shi...
Use of mini-CEX as a teaching learning method in physiology for undergraduate medical students
Background: Most of the assessments of medical students are at the end of the term or year leaving hardly any scope for feedback. Mini-clinical evaluation exercise (mini-CEX) is a hybrid tool that allows assessment as we...
Effect of eight-week core stabilization program on core muscle endurance and function in female staff nurses
Background: Low back pain is a widespread pain condition in the working population. Anticipatory postural adjustment of the transverses abdominis muscle has received particular interest for the research of postural contr...
A comparative experimental study of proconvulsive potential of ciprofloxacin and ofloxacin and assessment of proconvulsive potentiating action of caffeine coadministration with fluoroquinolones in rats
Background: Fluoroquinolones are one of the most common antimicrobials prescribed for a variety of infections. They have potential to lower seizure threshold. This can be harmful when prescribed to consumers of energy dr...