Determining the Phytochemical Constituents and the Antimicrobial Activity of Ethanolic Extract of Acassia Leaf (Senna Siamea) On Some Enterobacteriaceae
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2015, Vol 5, Issue 6
Abstract
ABSTRACT: Microorganisms are known to cause different types of infection in both humans and animals. The use of medicinal plants to prevent and treat such infections is increasing. This study was aimed at investigating the phytochemical constituents of ethanolic extract of Senna siamea leaf and also to determine its antimicrobial activity on some Enterobacteriaceae which include Escherichia coli, Proteus mirabilis and Klebsiella pneumonia, using agar disc diffusion method. The result revealed that the ethanolic extract of Senna siamea leaf inhibited the growth of these microorganisms to varying proportions with zones of inhibition ranging from 16 to 20 mm as lowest and highest zones of inhibition. Furthermore, the phytochemical screening of the leaf extract indicated the presence of alkaloids, flavonoids, steroids and tannins, while saponins were absence. The presence of alkaloids, flavonoids and tannins in the extracts could be responsible for the observed antimicrobial activity. Findings therefore, recommend the use of Senna siamea leaf in the treatment of enteric fever in traditional medicine.
Authors and Affiliations
Mansur Abdulrasheed *1, Ibrahim Hussein Isiaka 2 , and Ismail Ahmed Siddan3
Keywords
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