EFFECT OF TWO TYPES OF DIETARY GHEE ON SERUM LIPID LEVELS IN RATS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 49
Abstract
Ghee is also known as clarified butter, utilized for thousands of years in Ayurveda as a therapeutic agent. Ghee which is known as “Gritha” in Ayurveda, described as the best among lipid media due to its quality of inheriting and enhancing the drug potency. Even though ghee is an animal fat, earlier studies have shown that larger doses given for cleansing purpose did not increase the level of Low Density Lipoprotein (LDL). Instead increased High Density Lipoprotein (HDL) or some time did not alter lipid profile at all. Earlier studies in rats, which were fed up to 10% dietary ghee showed dose dependent decrease in cholesterol and other lipid profiles. There are two methods in preparation of butter. One is from milk cream, clarified butter and the other from curds, cultured butter. Butter will be further processed to convert it into ghee. None of the earlier studies have shown, which type of ghee is better and compared their effects on lipid profiles. So, our objective of the study was to know the effects of 5% and 10% milk cream ghee (Ghee from clarified Butter) and curd ghee (Ghee made out of Cultured Butter) supplementation on lipid profile in Wistar rats. So we supplied 5% and 10% dietary ghee in a nutritionally balanced diet to 8 weeks old male rats for 12 weeks and estimated Total cholesterol, HDL, LDL, Very Low Density Lipoprotein (VLDL) and Triglycerides (TGL) levels after 12 weeks. These results indicate that 5% and 10% of cream ghee and 10% curds ghee did increase body weight after 12 weeks of consumption and 5% curds ghee was found not to increase the body weight; 5% Curd Ghee has shown to lower total cholesterol, LDL, VLDL, triglycerides levels and cholesterol ratio more than other groups in our experimental model. HDL levels were increased in all the groups, which was not statistically significant in 5% cream and 5% curd ghee groups.
Authors and Affiliations
Karamaradi Nirmala, Bhat S, Sahajananda
Keywords
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- EP ID EP144149
- DOI 10.14260/jemds/2016/729
- Views 87
- Downloads 0
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