EVALUATION OF AETIOLOGICAL ROLE OF MISDIRECTED TOOTH IN THE INCIDENCE OF SQUAMOUS CELL CARCINOMA OF ORAL CAVITY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 51
Abstract
BACKGROUND The incidence and progression of the oral cancer varies according to various cultural and lifestyle factors. In India, tobacco usage in the form of smoked and non-smoked tobacco both is a common practice. In Western population smoking and alcohol consumption are the main risk factors. Studies have shown that there is also role of non-modifiable risks like HPV infections and chronic irritation by continuous trauma from misdirected tooth in causation of Oral Squamous Cell Carcinoma (OSCC). AIMS To find out the role played by chronic irritation due to misdirected tooth as an aetiological factor for OSCC. METHODS AND MATERIALS This is a retrospective clinical study done in 42 patients with OSCC from July 2014 to March 2016. RESULTS 23.8% patients who consumed alcohol and had misdirected tooth developed cancer, whereas only 4.76% patients with alcohol consumption history alone developed cancer; 26.19% patients used tobacco and had misdirected tooth developed cancer and only 7.14% with tobacco usage alone developed cancer. In 19.04% patients who took alcohol and tobacco both and with misdirected tooth developed cancers and in 7.14% cases developed cancer when there is only history of alcohol and tobacco usage alone and no misdirected tooth was present; 7.14% patients developed cancers only with the presence of misdirected tooth alone; 4.76% patients developed cancer de novo even with not any risk factor involved. CONCLUSION We came to the conclusion that there is a significant role of irritation by misdirected tooth in the causation of OSCC as well as it is a major synergistic factor when combined with tobacco and alcohol consumption
Authors and Affiliations
Jagdish Purohit, Sushil Kashyap, Manish , Siva , Chandrabhan , Vineet
GASTROINTESTINAL STROMAL TUMOUR – REVISITED
Although less common than epithelial neoplasms, mesenchymal tumours of GI tract are not rare. The main bulk of these mesenchymal tumours is formed by Gastrointestinal stromal tumors (GIST). However they are not...
IMAGING OF BREAST LESIONS USING CONVENTIONAL MAGNETIC RESONANCE IMAGING AND DIFFUSION WEIGHTED IMAGING
[b]CONTEXT:[/b] Breast cancer is the second most common cancer in the world, and the second most common in cancer in Indian women. [b]AIMS[/b]: The aims of this study were to differentiate between benign and...
A STUDY ON HYSTEROLAPAROSCOPY IN FEMALE INFERTILITY- A DIAGNOSTIC CUM THERAPEUTIC TOOL
BACKGROUND Infertility, according to WHO, is defined as “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.” Inf...
MICROANATOMIC STUDY OF HUMAN PANCREATIC ISLETS IN ALCOHOLICS AND NON-ALCOHOLICS- A DESCRIPTIVE COMPARATIVE STUDY
BACKGROUND The islets of Langerhans are an important endocrine gland, which regulate the blood glucose level. The rise in blood glucose level results in diabetes mellitus, an age-old disease which affects all the systems...
NON-OPERATIVE MANAGEMENT OF BLUNT HEPATIC AND/OR SPLENIC TRAUMA: A PROSPECTIVE STUDY
[b] PURPOSE[/b]: The incidence of blunt splenic and hepatic injuries are on a rise not only because of an increase in the overall incidence of Road Traffic Accidents but also due to more liberal use of radiolog...