Evaluation of immune status of young female during different phases of menstrual cycle
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2015, Vol 5, Issue 4
Abstract
Back ground: Menstruation is characterized by monthly rhythmical changes in the rates of secretion of the female sex hormones and corresponding physical changes in the ovaries and other sexual organs. There are three phases of menstrual cycle namely, menstrual phase, proliferative phase, and secretary phase. There occur fluctuations in the levels of sex steroid hormones across different phases of menstrual cycle. Aims and objectives: This study was carried out to evaluate the immune response of healthy female students of first–year MBBS (n = 40) in the age group of 18–25 years with regular menstrual cycle. Materials and Methods: The parameters analyzed were total leukocyte count (TLC); absolute eosinophil count (AEC); and differential leukocyte count (DLC) of neutrophils, lymphocytes, monocytes, eosinophil, and basophils. The data collected were statistically analyzed. Result: There was significant increase in TLC during menstrual and secretary phase of menstrual cycle. No significant difference was observed in AEC during different phases of menstrual cycle. In DLC, there was a significant increase in the neutrophil percentage during secretary phase. Lymphocyte count increased during proliferative and secretary phase but it is not statistically significant. No significant difference was observed in monocyte and eosinophil count. Conclusion: This study shows normal variation in the leucocyte count during different phases of menstrual cycle that may help in understanding various disorders.
Authors and Affiliations
Rekha Jiwane, Tanwir Alam, Arbind Kumar Choudhary, Sadawarte Sahebrao Kishanrao, Vivekanand Gajbhiye
Keywords
Related Articles
- EP ID EP128430
- DOI 10.5455/njppp.2015.5.2705201551
- Views 59
- Downloads 0
Effect of non-absorbable antibiotic, rifaximin in patients with irritable bowel syndrome: A single-center randomized controlled study
Background: Irritable bowel syndrome (IBS), most common functional bowel disease, does not have a definite treatment. Studies revealed the involvement of bacterial overgrowth for its pathology. The aim of this study is t...
Lipid profile and its relationship with blood glucose levels in Metabolic Syndrome
Background: Metabolic syndrome (MetS) and its associated factors such as dyslipidemia and hyperglycemia are associated with increased risk of cardiovascular disease (CVD). Aims and Objective: To assess lipid prof...
A comparative analysis of cardiovascular response to stress in menstrual and follicular phase in medical students
Background: Autonomic function tests based on cardiovascular responses to stressors are simple and non-invasive methods to help the clinician to make a proper assessment of the state of autonomic nervous system so as to...
Relationship of dynamic lung function parameters in pregnant women with different degrees of anemia: A cross-sectional study in Odisha
Background: Anemia has potential adverse effects on mother and fetus. Moderate-to-severe anemia in pregnancy reduces diaphragmatic strength and leads to exertional dyspnea. Aims and Objective: In the present study, we tr...
Anti inflammatory property of salbutamol on acute and chronic models of inflammation
Background: β2-Adrenergic receptor agonist agents were able to suppress the immune response by inhibiting release of IL-12 and production of TNF-α by the direct stimulation of β-adrenergic receptors on inflammator...