Evaluation of lipid parameters and family history of diabetes mellitus in polycystic ovary syndrome
Journal Title: Dicle Tıp Dergisi - Year 2013, Vol 40, Issue 3
Abstract
In the present study we investigated lipid parameters of Polycystic Ovary Syndrome (PCOS) patients and Diabetes Mellitus (DM) history of their family and relatives. Methods: In this cross-sectional study, one hundred and twenty patients with PCOS and 30 healthy controls were involved at Erzurum Research and Training Hospital. History, Body mass index (BMI), ultrasonography findings, blood hormone profiles (Follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), thyroidstimulating hormone (TSH), total and free testosterone (Total-T and Free-T), prolactin (PRL)), and serum lipids (total cholesterol (Total-C), high-density cholesterol (HDLC), low-density cholesterol (LDL-C), and triglycerides (TG), fasting blood glucose and plasma insulin level were measured. HOMA-IR (Homeostatic model assessmentinsulin resistance) was calculated. Results: DM history in the family was found in 29 (24%) of PCOS patients and 2 (6%) of healthy controls. The difference between groups was statistically significant (p<0.05). DM history in the relatives was determined in 45 (35%) PCOS patients and 5 (17%) controls. The difference between groups was statistically significant (p<0.05). HOMA-IR, fasting glucose and insulin levels were significantly higher in PCOS patients (p<0.05). Lipid parameters were not significantly different between the two groups. Conclusion: Frequency of DM in the family and relatives of PCOS patients was significantly more common than controls. In contrast to previous studies, no deterioration was found in lipid parameters in patient with PCOS. Key words: PCOS, Family history, DM, lipid parameters
Authors and Affiliations
İlay Gözükara, Eda Uludağ, Suna Kucur, Havva Yılmaz, Ayşe Çarlıoğlu
Keywords
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- EP ID EP146530
- DOI 10.5798/diclemedj.0921.2013.03.0300
- Views 103
- Downloads 0
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