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 Evaluation of SicA gene elimination from Salmonella enteritidis as a candidate for gene vaccine

Journal Title: International Journal of Advanced Biotechnology and Research. - Year 2016, Vol 7, Issue 1

Abstract

 ABSTRACT: Salmonella is a facultative intracellular pathogen which is serotype and host-dependent and can cause diseases from brain inflammation to typhoid fever. SicA is one of the virulence genes of Salmonella. SicAcause activation of the transcription from SigD/sopB and sopE that code the secreted effective proteins encoding which cause increased invasion. The purpose of this study is creation of a gene quasi-structure for the elimination of SicA gene from Salmonella enteritidis. SicA gene of Salmonella enteritidis bacterium causes the elimination of this gene. This gene quasi-structure can be used for preparation of a weak strain as a candidate for gene vaccine against Salmonella enteritidis in the future researches

Authors and Affiliations

Mehdi Zarei3 , Zinat Mohammadi2 , Mohammadreza Gholami3 and Morteza Khani*1

Keywords

: Salmonella enteritidis SicA gene gene vaccine
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  • EP ID EP107206
  • DOI -
  • Views 97
  • Downloads 0

How To Cite

Mehdi Zarei3, Zinat Mohammadi2, Mohammadreza Gholami3 and Morteza Khani*1 (2016).  Evaluation of SicA gene elimination from Salmonella enteritidis as a candidate for gene vaccine. International Journal of Advanced Biotechnology and Research., 7(1), 59-63. https://europub.co.uk/articles/-A-107206

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