FLAVONOID GLYCOSIDE FROM THE ETHYL ACETATE EXTRACT OF KELADI TIKUS TYPHONIUM FLAGELLIFORME (LODD) BLUME LEAVES
Journal Title: ASIAN JOURNAL OF NATURAL & APPLIED SCIENCES - Year 2012, Vol 1, Issue 4
Abstract
A flavonoid glycoside has been isolated from keladi tikus (Typhonium flagelliforme (Lodd) Blume) leaves. Keladi tikus is a plant traditionally uses as anticancer. The ethyl acetate extract was isolated using Vacuum Liquid Chromatography, then fractionated with column chromatography and identified by UV-VIS, FTIR, LCMS-MS and 1H-NMR, 13C-NMR, 2D-NMR (HMQC, HMBC, DEPT and COSY). The result from the isolation of the ethyl acetate fraction T. flagelliforme (Lodd) Blume obtained 6-glucosyl apigenine namely isovitexin. Isovitexin has antioxidant activity (DPPH free radical scavenging) with IC50 34.39 μg/mL and cytotoxic activity using BSLT (LC50 15.84 μg/mL).
Authors and Affiliations
Yunahara Farida, P. S. Wahyudi, S. Wahono, M. Hanafi
Keywords
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