FLAVONOID GLYCOSIDE FROM THE ETHYL ACETATE EXTRACT OF KELADI TIKUS TYPHONIUM FLAGELLIFORME (LODD) BLUME LEAVES

Journal Title: ASIAN JOURNAL OF NATURAL & APPLIED SCIENCES - Year 2012, Vol 1, Issue 4

Abstract

 A flavonoid glycoside has been isolated from keladi tikus (Typhonium flagelliforme (Lodd) Blume) leaves. Keladi tikus is a plant traditionally uses as anticancer. The ethyl acetate extract was isolated using Vacuum Liquid Chromatography, then fractionated with column chromatography and identified by UV-VIS, FTIR, LCMS-MS and 1H-NMR, 13C-NMR, 2D-NMR (HMQC, HMBC, DEPT and COSY). The result from the isolation of the ethyl acetate fraction T. flagelliforme (Lodd) Blume obtained 6-glucosyl apigenine namely isovitexin. Isovitexin has antioxidant activity (DPPH free radical scavenging) with IC50 34.39 μg/mL and cytotoxic activity using BSLT (LC50 15.84 μg/mL).

Authors and Affiliations

Yunahara Farida, P. S. Wahyudi, S. Wahono, M. Hanafi

Keywords

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  • EP ID EP125199
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How To Cite

Yunahara Farida, P. S. Wahyudi, S. Wahono, M. Hanafi (2012).  FLAVONOID GLYCOSIDE FROM THE ETHYL ACETATE EXTRACT OF KELADI TIKUS TYPHONIUM FLAGELLIFORME (LODD) BLUME LEAVES. ASIAN JOURNAL OF NATURAL & APPLIED SCIENCES, 1(4), 16-21. https://europub.co.uk/articles/-A-125199