FOURNIER’S GANGRENE: A MICROBIOLOGICAL OVERVIEW
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 1
Abstract
Fournier’s gangrene (FG) is a rare, rapidly progressive, fulminant form of necrotizing fasciitis of the genital, perianal and perineal region and is usually secondary to polymicrobial infection. OBJECTIVES Presently, the literature regarding the spectrum of pathogens causing FG is limited. Hence, this study was undertaken to get a better understanding of (a) Microbial pathogens causing FG and (b) The clinical outcome. METHODS The present study is a retrospective cohort study of the microbial pathogens isolated from FG patients admitted in a tertiary care centre. Data was collected from the hospital records of patients admitted with FG during June 2012 to November 2015. RESULTS A total of 55 male patients with FG were included in this study. The mean age of patient was 49.36 years. Out of 55 samples, 47- showed evidence of microbial growth, 12 samples showed mono-microbial and 35 samples showed poly-microbial growth. Among the cases included in the present study, anaerobic culture was requested for only 10 samples; 3 out of the 10 samples subjected to anaerobic culture yielded Bacteroides fragilis (B. fragilis). Klebsiella pneumoniae was the most common pathogen isolated (K. pneumoniae) (29/47, 61.70%), followed by Enterococcus faecalis (E. faecalis) (15/47, 31.91%), B. fragilis (3/10, 30%) and Escherichia coli (E. coli) (13/47, 27.65%). Gram negative organisms were highly susceptible to levofloxacin and piperacillin– tazobactam. Gram positive organisms were highly susceptible to linezolid (92%), vancomycin (84%) and tetracycline (68%). Major risk factors associated with FG were diabetes (43.6%) and obesity (40%). The mortality rate was 5.45%. CONCLUSION FG is a rapidly progressive fulminant life threatening condition. Early diagnosis, aggressive surgical intervention and appropriate antimicrobial therapy may help to reduce the mortality rate.
Authors and Affiliations
Anjana Gopi , Vinoba S, Neetha Murthy, Swati Jain, Faiza Samreen
Keywords
Related Articles
- EP ID EP143998
- DOI 10.14260/jemds/2016/10
- Views 104
- Downloads 0
A RARE CASE OF PENETRATING FISH-HOOK INJURY TO THE EYE WITH GOOD VISUAL OUTCOME
PRESENTATION OF CASE A 15-year-old boy presented to the emergency department with history of having gone fishing 3 hours prior and in the process of drawing the fish the hook got accidentally lodged in his right eye. The...
OVERVIEW OF GESTATIONAL DIABETES MELLITUS AND ITS EFFECT ON MATERNAL, FOETAL AND NEONATAL OUTCOME
BACKGROUND The incidence varies considerably from 1 - 14%, depending upon ethnicity, selection criteria and diagnostic tests performed. GDM affects the index pregnancy as well as two generations, mother and her child. Sh...
ILEAL GIST – CASE REPORT AND REVIEW OF LITERATURE
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract (GIT). They can arise anywhere along the gastrointestinal tract. GIST of the small bowel is less common. Cli...
ADENOID CYSTIC CARCINOMA OF THE LARYNX: AN UNIQUE PRESENTATION
A 40 year male patient presented to us with the history of having coughed out moderate quantities of blood on two occasions during the preceding week. During one episode he had coughed out a piece of tissue as well....
A CASE OF INCARCERATED EPIGASTRIC HERNIA IN AN ADULT MALE
PRESENTATION OF CASE A 45-year-old, male patient was admitted to our hospital 3 hours after the sudden onset of abdominal pain. His epigastric region had a swelling and he was diagnosed with an irreducible epigastric her...