Host Modulation- Promising Direction In Periodontal Therapy
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2014, Vol 4, Issue 2
Abstract
: The primary etiology of the periodontal disease is chronic inflammation due to bacterial infection. It is the host’s reaction to the presence of bacteria that mediates tissue destruction .Since the destruction of periodontium is believed to be due to the host response , it is intellectual and logical to consider therapeutic approaches that modulate the host response in addition to antibacterial approaches in periodontal therapy. Improved knowledge of bacterium –host interactions and of the process leading to tissue destruction will help to identify targets for host modulation to reduce periodontitis in selected situations .The objective of this article is to review and update the fundamental scientific concepts of host modulation and to furnish an approach to the main types of therapy used, based on the scientific literature.
Authors and Affiliations
Dr. Priyadarshni Rangarajan , Dr. Hariharavel Vp , Dr. Ieshwaryah Kumanan
Keywords
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