KALA-AZAR MIMICKING CHRONIC LIVER DISEASE- A RARE PRESENTATION. A CASE FROM SIKKIM (NORTH-EASTERN STATE)
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 21
Abstract
Visceral leishmaniasis, also known as kala-azar, is a vector borne disease caused by the protozoan parasite, L. donovani. [1] Visceral leishmaniasis is prevalent worldwide. [2] India is one of the countries that account for an estimated 300,000 of 500,000 cases of visceral leishmaniasis (VL) occurring annually. State of Bihar is the most affected area in India, with more than 90% of the cases, [3] and to some extent in its bordering states like West Bengal and Uttar Pradesh. [4] Functional derangement of liver in visceral leishmaniasis is reported infrequently in the literature, due to this, many cases are wrongly diagnosed and treated as hepatitis. [5] Common clinical manifestations are fever (99%), splenomegaly (99%), anaemia (96%), hepatomegaly (86%), distension of abdomen (47%), bleeding diathesis (14%) and pancytopenia. [6] There are case reports of visceral leishmaniasis mimicking portal hypertension, and it has been suggested that screening of the disease in children presenting with chronic liver disease is important in endemic areas. [7] Certain unusual clinical and laboratory features were seen in some of the reported cases, like lymphadenopathy, nasopharyngeal growth, acute and chronic hepatic involvement and portal hypertension. [8] One case reported from India has shown visceral leishmaniasis masquerading as chronic liver disease with abdominal doppler study revealing portal hypertension and endoscopy showing grade II oesophageal varices. [9] Sikkim is not an endemic area for kala-azar and only few sporadic cases are been reported from the state.
Authors and Affiliations
Mona Dhakal, Dhakal O. P
Keywords
Related Articles
- EP ID EP138167
- DOI 10.14260/jemds/743
- Views 104
- Downloads 0
AN OVARIAN STEROID CELL TUMOUR CAUSING VIRILISATION- A RARE CASE REPORT
Steroid cell tumor of the ovary a very rare androgen secreting tumor accounts for less than 0.1% of ovarian tumors. These tumors may present at any age ranging from 2 to 80 yrs & associated with hormonal ac...
SPECTRUM OF CARCINOMA GALLBLADDER
BACKGROUND Carcinoma of gallbladder is uncommon but is a highly fatal malignancy due to late presentation. However, it is the most common malignancy of biliary tract and represents 80-90% of the biliary tract complicatio...
PATTERN OF FATAL CHEST INJURY DUE TO ROAD TRAFFIC ACCIDENTS IN BIHAR STATE
Bihar is relatively a backward state of India where deaths due to chest injuries in road traffic accidents are very common. Deaths due to chest injuries could be more preventable and treatable than head injuries...
“STUDY OF LARGE BOWEL OBSTRUCTION IN ADULTS”
[b]AIM[/b]: To study the Incidence, Etiology, Clinical features, Investigations undertaken to arrive at Diagnosis, Treatment and Post-operative outcomes of large bowel obstruction in adults. [b]METHODS[/b]: Thi...
A CASE OF RECURRENCE OF MPNST IN NF 1 WITH INTRACRANIAL AND HEPATIC METASTASES
Neurofibromatoses Type 1(NF 1) is an autosomal dominant disease characterized by disordered growth of ectodermal tissues, and is part of a group of disorders called Phakomatoses (neurocutaneous syndrome). NF 1...