Nuclei segmentation of leukocytes in blood smear digital images
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2015, Vol 28, Issue 5
Abstract
The Leukocytes are differentiated from each other on the basis of their nuclei, demanded in many Medical studies, especially in all types of Leukemia by the Hematologists to note the disorder caused by specific type of Leukocyte. Leukemia is a life threatening disease. The work for diagnosing is manually carried out by the Hematologists involving much labor, time and human errors. The problems mentioned are easily addressed through computer vision techniques, but still accuracy and efficiency are demanded in terms of the basic and challenging step segmentation of Leukocyte’s nuclei. The underlying study proposed better method in terms of accuracy and efficiency by designing a dynamic convolution filter for boosting low intensity values in the separated green channel of an RGB image and suppressing the high values in the same channel. The high values in the green channel become 255 (background) while the nuclei always have low values in the green channel and thus clearly appear as foreground. The proposed technique is tested on 365 images achieving an overall accuracy of 95.89%, while improving the efficiency by 10%. The proposed technique achieved its targets in a realistic way by improving the accuracy as well as the efficiency and both are highly required in the area.
Authors and Affiliations
Naveed Abbas , Dzulkifli Mohamad , Abdul Hanan Abdullah , Tanzila Saba , Mznah Al-Rodhaan , Abdullah Al-Dhelaan
To study the influence of different grades of Ethylcellulose ether derivative polymer Ethocel® and co-excipient on drug release profile of controlled release matrix tablet of acarbose
The aim of the study presented is to formulate and evaluate Acarbose controlled release matrix tablets by means of different grades of polymer Ethocel and different co-excipients with the intention to see their eff...
Effects of probiotics on the growth performance and intestinal micro flora of broiler chickens
Antibiotics have been used in poultry industry for decades to promote growth and protect animals from diseases, followed by various side effects. In efforts of searching for a better alternative, probiotic is of ex...
Study on optimization of proportion between fermented liquid and traditional cultural medium of bioflocculant production and its flocculant performance considering the aerobic fermentation of rice straw as substrate
High cost of traditional culture medium of flocculant is the key element to limit the bioflocculant production. It’s therefore much crucial to seek the economic production materials. In this research, part of the t...
Localization of sulphonylurea receptor proteins SUR2A and SUR2B and/or SUR1 in rat kidney
To further explore precise expression and localization of sulphonylurea receptor isoforms SUR2A and SUR2B (SUR1) in rat kidney, total RNA was isolated from the kidney tissue using the TRIzol kit. Three different pr...
Combined use of borneol or menthol with labrasol promotes penetration of baicalin through rabbit cornea in vitro
The permeability of most drugs through the eyes is very limited, so finding safe and effective penetration enhancers is of high importance in current ophthalmology research. In this paper, we use a new approach tha...