OUTCOME OF VENTILATION IN HYALINE MEMBRANE DISEASE: THE INDIAN EXPERIENCE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 52
Abstract
OBJECTIVE To study the short-term outcome of both preterm and term babies requiring assisted ventilation for hyaline membrane disease and report the complications contributing to morbidity and mortality of these patients from a regional medical college with limited resources. DESIGN Retrospective file review. SETTING Regional Medical College. PARTICIPANTS All babies ventilated for HMD over a 6-year period from June 2008 to June 2014. OUTCOME MEASURES Outcome of ventilation and factors contributing to mortality. RESULTS Out of 100 babies with hyaline membrane disease who were ventilated, 82% survived. Increasing gestational age and birth weight was associated with survival. The commonest complication was shock (77%) and the commonest cause of mortality was septicaemia (77%). Septicaemia, Disseminated Intravascular Coagulation (DIC) and pulmonary haemorrhage were significantly more common complications babies who died (p<0.05). Binary logistic regression analysis showed that DIC (Odds ratio 5.2 [Confidence intervals (C.I.) 1.1-27.1]) and pulmonary haemorrhage (OR 18 [1.72-45.2]) to be predictors of mortality. The incidence of intraventricular haemorrhage was 1% and that of pneumothorax was 2%. The initial peak inspiratory pressure administered was significantly lower (p=0.033) and maximum peak end expiratory pressure was significantly higher in those who expired (p=0.027). CONCLUSION Outcome of ventilation for hyaline membrane disease improves with increasing gestational age and birth weight. The commonest cause of mortality and morbidity were septicaemia and shock respectively
Authors and Affiliations
Nayana P. C, Somasekharan K. S, Junaid M. I
Keywords
Related Articles
- EP ID EP90914
- DOI 10.14260/jemds/2016/780
- Views 118
- Downloads 0
MOBILE PHONE USERS AND ITS EFFECT OF HEARING IN TERMS OF DISTORTION PRODUCT OTOACOUSTIC EMISSION (DPOAE)
BACKGROUND Cellular phones/ mobile phones are the new addiction in today’s society. They can do pretty much everything from making calls to controlling remotely located devices/cameras. Mobile phones, owing to their user...
A RANDOMISED, DOUBLE-BLIND, PROSPECTIVE STUDY OF CAUDAL ROPIVACAINE VERSUS ROPIVACAINE WITH FENTANYL VERSUS ROPIVACAINE WITH NEOSTIGMINE FOR COMBINED EPIDURAL AND GENERAL ANAESTHESIA IN CHILDREN
BACKGROUND There are no studies comparing the outcomes of using Fentanyl or Neostigmine as adjuvants to Ropivacaine in terms of postoperative analgesia for paediatric caudal block. The aim of our study is to compare the...
MANAGEMENT OF HAEMORRHOIDS BY OPEN AND CLOSED HAEMORRHOIDECTOMY– A COMPARATIVE STUDY
BACKGROUND Haemorrhoids are estimated to affect nearly 40% of the population during their lifetime in some form or the other. Milder forms respond to conservative management whereas surgical approach is necessary in the...
A CLINICAL STUDY OF OTORHINOLARYNGOLOGICAL SYMPTOMS IN PREGNANCY
BACKGROUND Pregnancy is a period in women's life which needs special consideration in regard to healthcare of both the mother and the foetus. ENT symptoms have an impact on the quality of life during pregnancy. Our study...
SENSORY NERVE CONDUCTION VELOCITY IN SUBJECTS WITH IRON-DEFICIENCY ANAEMIA
BACKGROUND The predominant cause of anaemia in the general population is iron-deficiency anaemia, but there are little data about the peripheral nerve sensory function in subjects with iron-deficiency anaemia....