OUTCOME OF VENTILATION IN HYALINE MEMBRANE DISEASE: THE INDIAN EXPERIENCE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 52
Abstract
OBJECTIVE To study the short-term outcome of both preterm and term babies requiring assisted ventilation for hyaline membrane disease and report the complications contributing to morbidity and mortality of these patients from a regional medical college with limited resources. DESIGN Retrospective file review. SETTING Regional Medical College. PARTICIPANTS All babies ventilated for HMD over a 6-year period from June 2008 to June 2014. OUTCOME MEASURES Outcome of ventilation and factors contributing to mortality. RESULTS Out of 100 babies with hyaline membrane disease who were ventilated, 82% survived. Increasing gestational age and birth weight was associated with survival. The commonest complication was shock (77%) and the commonest cause of mortality was septicaemia (77%). Septicaemia, Disseminated Intravascular Coagulation (DIC) and pulmonary haemorrhage were significantly more common complications babies who died (p<0.05). Binary logistic regression analysis showed that DIC (Odds ratio 5.2 [Confidence intervals (C.I.) 1.1-27.1]) and pulmonary haemorrhage (OR 18 [1.72-45.2]) to be predictors of mortality. The incidence of intraventricular haemorrhage was 1% and that of pneumothorax was 2%. The initial peak inspiratory pressure administered was significantly lower (p=0.033) and maximum peak end expiratory pressure was significantly higher in those who expired (p=0.027). CONCLUSION Outcome of ventilation for hyaline membrane disease improves with increasing gestational age and birth weight. The commonest cause of mortality and morbidity were septicaemia and shock respectively
Authors and Affiliations
Nayana P. C, Somasekharan K. S, Junaid M. I
Keywords
Related Articles
- EP ID EP90914
- DOI 10.14260/jemds/2016/780
- Views 79
- Downloads 0
BATTERED BABY SYNDROME- A MISERABLE CAUSE OF CHILD DEATH
BACKGROUND One of the important and usual missed causes of paediatric traumas is child abuse. This ominous phenomenon, which can be presented physically, psychologically, sexually and emotionally has grown significantly...
TRANSFUSION TRANSMITTED HEPATITIS- A STUDY AMONG BLOOD DONORS
BACKGROUND WHO has aimed the global elimination of Hepatitis B and Hepatitis C by 2030. Hepatitis B and hepatitis C are the major causes of acute and chronic liver diseases and they usually spread via infected body fluid...
A CADAVERIC STUDY OF MORPHOLOGY OF HUMAN SPLEEN
BACKGROUND Elaborating morphology of spleen which includes its shape, fissures, notches and comparing it with the available literature of previous studies would be beneficial for academicians and clinicians. MATERIALS AN...
LEADERSHIP SKILLS IN DENTAL CURRICULUM- A REVIEW
BACKGROUND Dental profession is shaped by several forces in an ever-changing environment. Current focus on technical skills alone cannot prepare the student for a career in research, practice or other administrative posi...
INGUINAL HERNIOPLASTY USING EXTERNAL OBLIQUE APONEUROSIS VERSUS LICHTENSTEIN MESH HERNIOPLASTY- A COMPARATIVE STUDY
BACKGROUND Using synthetic prosthesis (mesh) during Lichtenstein mesh hernioplasty causes clinical problems, such as foreign body sensation in the groin, discomfort, abdominal wall stiffness, and migration of the mesh fr...