Pathogenesis, Diagnosis and Treatment of Vaginitis and Cervicitis in Clinical Practice
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2014, Vol 4, Issue 8
Abstract
Vulvovaginitis results with the loss of Lactobacillus-dominated normal vaginal flora,with the sexual activity pathogenic organisms are introduced into the vagina. Lactobacillus maintain normal vaginal pH of 3.5,and production of hydrogen peroxide which is bactericidal. Primarily vaginitis include three infections,trichomonaiasis,vulvovaginalcandidiasis, and bacterial vaginosis(BV),desquamative inflammatory vaginitis(DIV), associated with estrogen deficiency. Cervicitis primarilyendocervicitis caused by sexually transmittedpathogens.Vaginal pathogens include: Candidaalbicans, Trichomonasvaginalis,Neisseriagonorrhoeae,C.trichomatis,Gardnerrelavaginalis.Drugs of choice for candidiasis, Fluconazole 150mg orally in a single dose with vaginal preparations,and metronidazole for trichomoniasis.Patienthistory,complete examination,and laboratory tests are essential for diagnosis of vaginitis or cervicitis.
Authors and Affiliations
MurtazaMustafa , ,Bendaman B Yanggau , HelenLasimbang
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