Phylogenetic tree construction based on amino acid composition and nucleotide content of complete vertebrate mitochondrial genomes

Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2013, Vol 3, Issue 6

Abstract

 To evaluate the appropriateness of phylogenetic trees in biological evolution, we expanded a pre-existing baseline data set of randomly selected organisms by incorporating a collection of intentionally chosen organisms. Using two different clustering algorithms—Ward’s method and neighbor-joining—we constructed phylogenetic trees based on nucleotide sequences as well as amino acid composition and nucleotide content of complete mitochondrial genomes and 16S rRNA and NADH dehydrogenase subunit 5 genes. We compared classifications derived from cluster analyses with data based on mathematical calculations of complete mitochondrial genomes. Analyses of predicted amino acid composition from complete mitochondrial genomes and of 16S rRNA sequences clearly differentiated terrestrial and aquatic vertebrates. Although no truly representative phylogenetic tree exists, phylogenetic trees provide scientifically appropriate information about biological evolution.

Authors and Affiliations

Kenji Sorimachi Teiji Okayasu

Keywords

Related Articles

 Requesting a complete biosensor system in phyto-sourced drug discovery and development

 Constituents from plant origins constitute about 25% of prescribed drugs in modern medication library. But the time taken from discovery to reaching the clinical therapy for a new drug in this field is approximat...

 Detection of Insulin-Like Protein and Some Active Compounds in Bauhinia Variegata Linn. Leaf Ethanolic Extracts and the Effect in Reducing Blood Glucose Levels in Mice

 The study aims to detect the insulin-like protein and determine the active compounds in Bauhinia variegata L. leaves ethanolic extracts that help in reducing the blood glucose levels for white albino mice. The ch...

The evolution of anti tuberculosis treatment in newly diagnosis pulmonary tuberculosis patients.

: Tuberculosis (TB), which is one of the oldest diseases known to affect humans and is likely to have existed in prehominids, is a major cause of death worldwide. This disease is caused by bacteria of the Mycobacterium t...

Antimicrobial Potential and In Vitro Cytotoxicity Study of Tabernaemontana Divaricata (L.) Stem Bark Extract Against HEK 293 Cell Line

Resistance of antibiotics against pathogenic microbes is a growing clinical concern, and the spread of resistant strains worldwide has been discombobulating public health. The ability of most infectious microbes evolving...

 Significance of Serum Uric Acid Level in Patients of Stroke with Diabetes Mellitus

[b] INTRODUCTION:[/b] Some studies have linked serum uric acid with stroke in diabetes mellitus. But it is debated. Therefore, we propose to evaluate hyperuricemia as a risk factor for stroke in patients with diab...

Download PDF file
  • EP ID EP104180
  • DOI -
  • Views 147
  • Downloads 0

How To Cite

Kenji Sorimachi Teiji Okayasu (2013).  Phylogenetic tree construction based on amino acid composition and nucleotide content of complete vertebrate mitochondrial genomes. IOSR Journal of Pharmacy (IOSRPHR), 3(6), 51-60. https://europub.co.uk/articles/-A-104180