PHYTOCHEMICAL AND ANTIMICROBIAL ANALYSIS OF THE STEM BARK OF PTEROCARPUS SANTALINOIDES, (NTURU UKPA)
Journal Title: ASIAN JOURNAL OF NATURAL & APPLIED SCIENCES - Year 2012, Vol 1, Issue 3
Abstract
Sequel to the use of the stem bark of Pterocarpus Santalinoides (Nturu Ukpa) in traditional medicine the phytochemical and antimicrobial analysis of the stem back was undertaken. Qualitative and quantitative evaluation of the phytochemicals were made using standard methods. The microbiological analysis of water and ethanolic extracts of the sample were performed on some common microorganisms such as Salmonella species, Klebsiella Pneumonia, Escherichia Coli , Pseudomonas Aerugunosa using the disc diffusion method for the screening using nutrient agar for the in vitro antimicrobial activities . The results showed that the stem bark of Pterocarpus Santalinoides (Nturu Ukpa) is rich in bioactive substances such as alkaloids 1.01+0.05, flavonoids 6.7+0.02, tannins 8.53+0.48, saponins, 1.7+0.08, phenolics, 31.45+0.15, cyanogenic glycosides 1.52× 10-4+1.73×10-6. The antimicrobial analysis showed that the ethanolic extract was active against Klebsiella pneumonia, Salmonella spp. and Escherichia coli with percentage inhibitions of 25.8+0.83, 25.8+8.3×10-1 and 15.8+8.3×10-1 .respectively.The ethanolic extract did not show activity on staphococcus aureus and pseudomonas aeruginosa. The water extract was active against Pseudomonas aeuriginosa 19.2_+ 8.4×10-1. The results indicate that the plant stem bark have potential medicinal uses and the ethanolic and water extracts can protect against some common microorganisms.
Authors and Affiliations
Eze, S. O, Cornelius , C, Okereke H.C
Keywords
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