POSTOPERATIVE ANALGESIA WITH TRANSDERMAL DICLOFENAC VERSUS INTRAMUSCULAR DICLOFENAC – A COMPARATIVE STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 19
Abstract
[b] BACKGROUND[/b]: The search for an ideal drug for postoperative analgesia is ongoing. Diclofenac is commonly used drug for this purpose in different routes. AIMS: To compare the efficacy of transdermal diclofenac with intramuscular diclofenac for postoperative analgesia. [b]SETTINGS AND DESIGN[/b]: This prospective comparative study was conducted in the department of anaesthesiology in a medical college & general hospital. [b]METHODS AND MATERIALS[/b]: The study subjects were 200 patients of both sexes between 18-50 years of age who were scheduled for elective laparoscopic, gynaecological & orthopaedic surgeries on limb. They divided into two groups. Group I received intramuscular injection of diclofenac sodium (75mg) & Group II received transdermal diclofenac diethylamine patch (200mg per 75 sq.cm) postoperatively. The outcome measures were pain intesity, changes in vital parameters, requirment for rescue analgesia & adverse effects. [b]STATISTICAL ANALYSIS[/b]: Parametric data were analysed by using student t-test (unpaired). Non parametric data were analysed by using test of association (chi-square test). [b]RESULTS[/b]: The mean pain score was significantly high in intramuscular diclofenac group (Group I) in laparoscopic & gynaecological surgeries (P = 0.002). Though the mean pain score was different among two groups in orthopaedic surgeries it was not statistically significant (P = 0.377). There were no significant differences in vital parameters & adverse reactions in between two groups. The requirment of rescue anlgesia was significantly more in intramuscular diclofenac group (Group I). [b]CONCLUSIONS[/b]: Transdermal diclofenac is more effective in reducing the intensity of postoperative pain following laparoscopic & gynaecological surgeries but the effect is similar to intramuscular diclofenac in orthopedic limb surgeries
Authors and Affiliations
Soumya Samal, Saubhagya Jena, Basanta Behera
Keywords
Related Articles
- EP ID EP95573
- DOI 10.14260/jemds/706
- Views 80
- Downloads 0
PROTEUS SYNDROME
BACKGROUND Proteus syndrome is a rare disorder of patchy/mosaic postnatal overgrowth. Case Characteristics Patient presented with hemihypertrophy, hyperpigmented vascular and epidermal nevi, kyphoscoliosis, macr...
THE DEVELOPING HUMAN FOETUS- RELATIVE GROWTH OF UTERUS COMPARED TO OVARIES
BACKGROUND Uterus is a constituent of the internal female reproductive tract which develops from a paired paramesonephric duct, originating from coelomic epithelium extending beside the mesonephric ducts. The paired duct...
STUDY ON HAEMORRHAGE IN 1ST TRIMESTER OF PREGNANCY AND ITS EVALUATION BY TRANSVAGINAL SONOGRAPHY
BACKGROUND Vaginal bleeding in the first trimester of pregnancy is a common obstetric problem and causes worry and anxiety both to the patient and the obstetrician. The first twelve weeks of intrauterine life are the mos...
POSTOPERATIVE ANALGESIA WITH TRANSDERMAL DICLOFENAC VERSUS INTRAMUSCULAR DICLOFENAC – A COMPARATIVE STUDY
[b] BACKGROUND[/b]: The search for an ideal drug for postoperative analgesia is ongoing. Diclofenac is commonly used drug for this purpose in different routes. AIMS: To compare the efficacy of transdermal diclof...
MICROBIAL KERATITIS- MICROBIAL PATTERN IN A TERTIARY CARE CENTRE OF A METROPOLITAN CITY
BACKGROUND Microbial keratitis is a potentially vision threatening state requiring prompt diagnosis & treatment, and is a leading cause of preventable blindness. We wanted to study the spectrum and sensitivity of microbi...