PROGNOSTIC SIGNIFICANCE OF C-REACTIVE PROTEIN IN ACUTE STROKE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 53
Abstract
BACKGROUND Cerebrovascular stroke is one of the leading cause of death and disability. C-Reactive Protein is an inflammatory marker that is increased in stroke. We intended to study the role of CRP in predicting severity and short-term outcome in stroke patients. METHOD The study included 60 patients with acute stroke admitted within 24 hours of symptom onset. All patients were subjected to detailed history taking and neurological evaluation. Severity of stroke on admission was assessed with National Institute of Health Stroke Scale (NIHSS), while seven days later outcome was assessed with modified Rankin Score (mRS) and Barthel ADL Index (BI). CRP levels and CT Brain was done in all patients within 24 hours of admission. RESULTS The mean age of the patients was 62.53±9.54. We found that CRP levels on admission was higher in ischaemic stroke patients (Mean=8.56±3.51) and there was positive correlation between CRP levels and severity assessed by NIHSS (r=0.44; p=0.004). There was positive correlation between CRP levels and short-term outcome assessed by mRS (r=0.35; p value=0.022). However, there was no positive correlation between CRP levels and severity or outcome in haemorrhagic stroke patients. CONCLUSION CRP levels on admission is a predictor of severity and short-term outcome in ischaemic stroke, but not haemorrhagic stroke.
Authors and Affiliations
Philomena , Rangaswami , Arun Radhakrishnan
Keywords
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- EP ID EP133712
- DOI 10.14260/jemds/2016/818
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